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1.发明授权Conformable prostheses for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US09402719B2
公开(公告)日：2016-08-02
申请号：US13453623
申请日：2012-04-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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2.发明授权Two piece heart valves including multiple lobe valves and methods for implanting them 有权两片心脏瓣膜包括多瓣瓣和植入它们的方法公开(公告)号：US08083793B2
公开(公告)日：2011-12-27
申请号：US11069457
申请日：2005-02-28
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly including an annular prosthesis implantable within a biological annulus, a prosthetic valve including a multiple lobular shape for implantation above the biological annulus, and one or more connectors for securing the prosthetic valve to the annular prosthesis. A flexible sewing cuff extends radially from the annular prosthesis that is resiliently flexible for conforming to the multiple lobular shape of the prosthetic valve to enhance a seal between the prosthetic valve and the annular prosthesis. The sewing cuff may include a core resiliently conformable with anatomy surrounding the biological annulus and fabric covering at least a portion of the core.
摘要翻译： 一种心脏瓣膜组件，包括可植入生物环境内的环形假体，包括用于植入生物环空以上的多个小叶形状的假体瓣和用于将假体瓣固定到环形假体的一个或多个连接器。 弹性缝合针从弹性柔性的环形假体径向延伸，以符合人工瓣膜的多个小叶形状，以增强人造瓣膜和环形假体之间的密封。 缝合箍可以包括弹性地与包围生物环的解剖结构的芯和覆盖芯的至少一部分的织物。
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3.发明授权Conformable prosthesis for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US07717955B2
公开(公告)日：2010-05-18
申请号：US11069081
申请日：2005-02-28
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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4.发明授权公开(公告)号：US08211169B2
公开(公告)日：2012-07-03
申请号：US11420720
申请日：2006-05-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412
摘要： A heart valve assembly includes a prosthesis for receiving a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus adjacent a sinus cavity. The prosthesis includes an annular member implantable within the biological annulus for contacting tissue surrounding the biological annulus to provide an opening through the biological annulus, a collar extending upwardly from the annular member, and a sewing cuff extending radially outwardly from the annular member and/or collar. Optionally, the annular member and/or collar may be resiliently compressible, expandable, and/or otherwise biased. A valve member, e.g., a mechanical or bioprosthetic valve may be coupled to the collar, e.g., using a drawstring, sutures, or other connectors, to secure the valve member to the gasket member.
摘要翻译： 心脏瓣膜组件包括用于接收假体瓣膜的假体，以替代邻近窦腔的生物环空中的预先存在的天然或假体心脏瓣膜。 假体包括可植入生物环境内的环形构件，用于接触围绕生物环的组织以提供通过生物环空的开口，从环形构件向上延伸的环和从环形构件径向向外延伸的缝合口和/或 领。 可选地，环形构件和/或套环可以是可弹性压缩的，可膨胀的和/或以其它方式偏置的。 阀构件，例如机械或生物假肢阀可以例如使用束带，缝合线或其它连接器联接到套环，以将阀构件固定到垫圈构件。
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5.发明申请CONFORMABLE PROSTHESES FOR IMPLANTING TWO-PIECE HEART VALVES AND METHODS FOR USING THEM 有权用于植入两片心脏瓣膜的一致性优势和使用它们的方法公开(公告)号：US20100191327A1
公开(公告)日：2010-07-29
申请号：US12754596
申请日：2010-04-05
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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6.发明授权Conformable prostheses for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US08163014B2
公开(公告)日：2012-04-24
申请号：US12754596
申请日：2010-04-05
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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7.发明申请Conformable Prostheses For Implanting Two-Piece Heart Valves and Methods for Using Them 审中-公开用于植入两片心脏瓣膜的适形假体及其使用方法公开(公告)号：US20120226348A1
公开(公告)日：2012-09-06
申请号：US13453623
申请日：2012-04-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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8.发明授权Connection systems for two piece prosthetic heart valve assemblies and methods for making and using them 有权用于两件式假体心脏瓣膜组件的连接系统及其制造和使用方法公开(公告)号：US08323337B2
公开(公告)日：2012-12-04
申请号：US12477861
申请日：2009-06-03
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2415 , A61F2/2418 , A61F2250/006
摘要： A heart valve assembly includes a prosthesis and a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus. The prosthesis includes an annular member, a flexible core at least partially defining a sewing cuff extending radially outwardly from the annular member, a rail ring disposed between the flexible core and the annular member, and a plurality of guide rails extending from the rail ring through respective openings in the flexible core. A fabric covering covers the prosthesis, and the guide rails extend through respective openings in the fabric covering. The prosthetic valve includes a frame including receptacles for receiving respective guide rails. After implanting the prosthesis within a biological annulus, the prosthetic valve is advanced along the guide rails until retention elements on the guide rails engage the receptacles to secure the prosthetic valve relative to the prosthesis.
摘要翻译： 心脏瓣膜组件包括假体和假体瓣膜，以替代生物环内的预先存在的天然或假体心脏瓣膜。 所述假体包括环形构件，柔性芯，至少部分地限定从所述环形构件径向向外延伸的缝合箍，设置在所述柔性芯和所述环形构件之间的轨道环，以及从所述轨道环延伸穿过的多个导轨 柔性芯中的相应开口。 织物覆盖物覆盖假体，并且导轨延伸穿过织物覆盖物中的相应开口。 假体瓣膜包括框架，该框架包括用于接收相应导轨的插座。 在将假体植入生物环境之后，人造瓣膜沿着导轨前进，直到导轨上的保持元件接合插座以相对于假体固定人造瓣膜。
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9.发明申请CONNECTION SYSTEMS FOR TWO PIECE PROSTHETIC HEART VALVE ASSEMBLIES AND METHODS FOR MAKING AND USING THEM 有权用于两个前置式心脏瓣膜组件的连接系统及其制造和使用它们的方法公开(公告)号：US20090319038A1
公开(公告)日：2009-12-24
申请号：US12477861
申请日：2009-06-03
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2415 , A61F2/2418 , A61F2250/006
摘要： A heart valve assembly includes a prosthesis and a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus. The prosthesis includes an annular member, a flexible core at least partially defining a sewing cuff extending radially outwardly from the annular member, a rail ring disposed between the flexible core and the annular member, and a plurality of guide rails extending from the rail ring through respective openings in the flexible core. A fabric covering covers the prosthesis, and the guide rails extend through respective openings in the fabric covering. The prosthetic valve includes a frame including receptacles for receiving respective guide rails. After implanting the prosthesis within a biological annulus, the prosthetic valve is advanced along the guide rails until retention elements on the guide rails engage the receptacles to secure the prosthetic valve relative to the prosthesis.
摘要翻译： 心脏瓣膜组件包括假体和假体瓣膜，以替代生物环内的预先存在的天然或假体心脏瓣膜。 所述假体包括环形构件，柔性芯，至少部分地限定从所述环形构件径向向外延伸的缝合箍，设置在所述柔性芯和所述环形构件之间的轨道环，以及从所述轨道环延伸穿过的多个导轨 柔性芯中的相应开口。 织物覆盖物覆盖假体，并且导轨延伸穿过织物覆盖物中的相应开口。 假体瓣膜包括框架，该框架包括用于接收相应导轨的插座。 在将假体植入生物环境之后，人造瓣膜沿着导轨前进，直到导轨上的保持元件接合插座以相对于假体固定人造瓣膜。
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10.发明申请公开(公告)号：US20110283514A1
公开(公告)日：2011-11-24
申请号：US13197364
申请日：2011-08-03
IPC分类号： B23P11/00
CPC分类号： A61F2/2412 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2409 , A61F2/2415 , A61F2002/30545 , A61F2250/001 , Y10T29/49826
摘要： Devices for fixturing a prosthesis to a first mass and methods of making and using the same are disclosed. Complementary fixturing devices and methods of making and using the same are also disclosed. The devices can be used to attach a heart valve gasket body to a biological annulus.
摘要翻译： 公开了将假体固定到第一质量块的装置及其制造和使用方法。 还公开了互补固定装置及其制造和使用方法。 该装置可用于将心脏瓣膜垫片主体附接到生物环。
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