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1.发明授权公开(公告)号：US08211169B2
公开(公告)日：2012-07-03
申请号：US11420720
申请日：2006-05-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412
摘要： A heart valve assembly includes a prosthesis for receiving a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus adjacent a sinus cavity. The prosthesis includes an annular member implantable within the biological annulus for contacting tissue surrounding the biological annulus to provide an opening through the biological annulus, a collar extending upwardly from the annular member, and a sewing cuff extending radially outwardly from the annular member and/or collar. Optionally, the annular member and/or collar may be resiliently compressible, expandable, and/or otherwise biased. A valve member, e.g., a mechanical or bioprosthetic valve may be coupled to the collar, e.g., using a drawstring, sutures, or other connectors, to secure the valve member to the gasket member.
摘要翻译： 心脏瓣膜组件包括用于接收假体瓣膜的假体，以替代邻近窦腔的生物环空中的预先存在的天然或假体心脏瓣膜。 假体包括可植入生物环境内的环形构件，用于接触围绕生物环的组织以提供通过生物环空的开口，从环形构件向上延伸的环和从环形构件径向向外延伸的缝合口和/或 领。 可选地，环形构件和/或套环可以是可弹性压缩的，可膨胀的和/或以其它方式偏置的。 阀构件，例如机械或生物假肢阀可以例如使用束带，缝合线或其它连接器联接到套环，以将阀构件固定到垫圈构件。
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2.发明申请CONFORMABLE PROSTHESES FOR IMPLANTING TWO-PIECE HEART VALVES AND METHODS FOR USING THEM 有权用于植入两片心脏瓣膜的一致性优势和使用它们的方法公开(公告)号：US20100191327A1
公开(公告)日：2010-07-29
申请号：US12754596
申请日：2010-04-05
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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3.发明授权Conformable prostheses for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US08163014B2
公开(公告)日：2012-04-24
申请号：US12754596
申请日：2010-04-05
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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4.发明申请Conformable Prostheses For Implanting Two-Piece Heart Valves and Methods for Using Them 审中-公开用于植入两片心脏瓣膜的适形假体及其使用方法公开(公告)号：US20120226348A1
公开(公告)日：2012-09-06
申请号：US13453623
申请日：2012-04-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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5.发明授权Conformable prostheses for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US09402719B2
公开(公告)日：2016-08-02
申请号：US13453623
申请日：2012-04-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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6.发明授权Two piece heart valves including multiple lobe valves and methods for implanting them 有权两片心脏瓣膜包括多瓣瓣和植入它们的方法公开(公告)号：US08083793B2
公开(公告)日：2011-12-27
申请号：US11069457
申请日：2005-02-28
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly including an annular prosthesis implantable within a biological annulus, a prosthetic valve including a multiple lobular shape for implantation above the biological annulus, and one or more connectors for securing the prosthetic valve to the annular prosthesis. A flexible sewing cuff extends radially from the annular prosthesis that is resiliently flexible for conforming to the multiple lobular shape of the prosthetic valve to enhance a seal between the prosthetic valve and the annular prosthesis. The sewing cuff may include a core resiliently conformable with anatomy surrounding the biological annulus and fabric covering at least a portion of the core.
摘要翻译： 一种心脏瓣膜组件，包括可植入生物环境内的环形假体，包括用于植入生物环空以上的多个小叶形状的假体瓣和用于将假体瓣固定到环形假体的一个或多个连接器。 弹性缝合针从弹性柔性的环形假体径向延伸，以符合人工瓣膜的多个小叶形状，以增强人造瓣膜和环形假体之间的密封。 缝合箍可以包括弹性地与包围生物环的解剖结构的芯和覆盖芯的至少一部分的织物。
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7.发明授权Conformable prosthesis for implanting two-piece heart valves and methods for using them 有权用于植入两件式心脏瓣膜的适形假体及其使用方法公开(公告)号：US07717955B2
公开(公告)日：2010-05-18
申请号：US11069081
申请日：2005-02-28
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2210/009 , A61F2220/0016 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.
摘要翻译： 心脏瓣膜组件包括环形假体和瓣膜假体。 环形假体包括用于扩张生物环境内的组织的环形环和从环形构件径向延伸的适形的缝合箍。 瓣膜假体包括框架和阀部件。 将环形环引入生物环中以扩张生物环带周围的组织，缝合箍符合生物环带上方的组织。 紧固件被引导通过缝合箍，以将环形假体固定到生物环。 环形假体可以包括用于在环形环上向外偏压织物以增强针对生物环空的密封的打孔元件。 然后，瓣膜假体前进到窦腔中，并相对于环形假体固定。 缝合袖口可以增强瓣膜假体和环形假体之间的密封。
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公开(公告)号：US20100070029A1
公开(公告)日：2010-03-18
申请号：US12574611
申请日：2009-10-06
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2250/006 , A61F2250/0097 , A61F2250/0098
摘要： A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
摘要翻译： 心脏瓣膜组件包括在平面内包括多小叶状环状的基部，阀构件或包括与基部的形状互补的多小叶形状的其它环形体，以及基部和环形体上的配合连接器， 将环形体连接到基座。 底座包括一个固定环，和一个用于将基座连接到生物环的柔性箍。 基部和环形体包括用于对准其多小叶形状的引导件，例如从底部延伸的视觉，触觉或其它标记或系绳，其可滑动通过环形体。 在使用过程中，基座附接到生物环形区域，环形体被定向成邻近环形区域，定向成使得环形体阀构件的多小叶形状与基部对准，并且环形体附接到基部 。
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公开(公告)号：US08603161B2
公开(公告)日：2013-12-10
申请号：US12498195
申请日：2009-07-06
IPC分类号： A61B17/10
CPC分类号： A61B17/064 , A61B17/0682 , A61B17/083 , A61B17/1227 , A61B2017/0641 , A61F2/2427 , Y10S623/904
摘要： Devices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound closure or a variety of other procedures such as anchoring a prosthesis to surrounding tissue or another prosthesis, tissue repair, such as in the closure of congenital defects such as septal heart defects, tissue or vessel anastomosis, fixation of tissue with or without a reinforcing mesh for hernia repair, orthopedic anchoring such as in bone fusing or tendon or muscle repair, ophthalmic indications, laparoscopic or endoscopic tissue repair or placement of prostheses, or use by robotic devices for procedures such as those above performed remotely.
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10.发明授权公开(公告)号：US08147504B2
公开(公告)日：2012-04-03
申请号：US12115543
申请日：2008-05-05
CPC分类号： A61B17/0684 , A61B17/00234 , A61B17/064 , A61B17/1222 , A61B17/1227 , A61B2017/00473 , A61B2017/0053 , A61B2017/00544 , A61B2017/00862 , A61F2/2409
摘要： A fastener delivery tool includes a belt including pairs of features for releasably engaging tines of respective fasteners in a relaxed state defining a loop. The tool includes a loading chamber for receiving a fastener from the belt, a retaining member for limiting movement of the fastener within the loading chamber, an ejection track communicating with the loading chamber, a handle including an actuator, and a tongue and pusher member coupled to the actuator. Activation of the actuator advances the tongue to transform the fastener from the relaxed state to a U-shaped constrained state, and advances the pusher member to direct the fastener from the loading chamber down the ejection track.
摘要翻译： 紧固件输送工具包括一带包括成对的特征，用于以松弛状态可释放地接合相应的紧固件的尖齿来限定环。 该工具包括用于从皮带接收紧固件的装载室，用于限制紧固件在装载室内的运动的保持构件，与装载室连通的排出轨道，包括致动器的手柄以及联接 到致动器。 致动器促使舌头将紧固件从松弛状态转变成U形的受限状态，并推进推动器构件以将紧固件从装载室向下排出。
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