NITRIC OXIDE-RELEASING POLYMERS
    1.
    发明申请
    NITRIC OXIDE-RELEASING POLYMERS 审中-公开
    氮氧化物释放聚合物

    公开(公告)号:US20110059036A1

    公开(公告)日:2011-03-10

    申请号:US12940208

    申请日:2010-11-05

    摘要: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.

    摘要翻译: 本发明涉及包含与释放一氧化氮(NO)的疏水性聚合物连接的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二聚物在生理条件下自发释放NO,而不产生亚硝胺形成。 本发明还涉及制备碳基二氮烯二烯聚合物的方法,包含这种聚合物的组合物,使用这种组合物的方法,以及使用这种聚合物组合物的装置。