公开(公告)号：US11169073B2

公开(公告)日：2021-11-09

申请号：US16422814

申请日：2019-05-24

Applicant: Essen Instruments, Inc.

Inventor： Stephen Barnes ,  Zachary Kane ,  Richard Bennett ,  Jason Barrett

IPC: G01N15/14 ,  G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  B01F11/00

Abstract: The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight.

公开(公告)号：US20200371012A1

公开(公告)日：2020-11-26

申请号：US16422814

申请日：2019-05-24

Applicant: Essen Instruments, Inc. d/b/a Essen BioScience, Inc.

Inventor： Stephen Barnes ,  Zachary Kane ,  Richard Bennett ,  Jason Barrett

IPC: G01N15/14 ,  G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  B01F11/00

Abstract: The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight.

公开(公告)号：US11137336B2

公开(公告)日：2021-10-05

申请号：US16175963

申请日：2018-10-31

Applicant: Essen Instruments, Inc.

Inventor： Stephen Barnes

IPC: G01N15/00 ,  G01N15/14 ,  G01N1/14

Abstract: A flow cytometer module configured to be integrated with a liquid handling system is provided herein. The flow cytometer module includes (a) a flow cell, (b) a first fluidic pathway, (c) an inlet configured to receive a sample introduction device of the liquid handling system including one or more samples, (d) a second fluidic pathway in fluid communication with the first fluidic pathway, (e) a laser interrogation device configured to examine the one or more samples at a laser interrogation point in the second fluidic pathway, and (f) a controller in communication with the liquid handling system and configured to cause the flow cytometer module to perform functions comprising: (i) recording data from the laser interrogation device corresponding to a plurality of events as the one or more samples pass the laser interrogation point, and (ii) transmitting the data corresponding to the plurality of events to the liquid handling system.