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1.发明授权公开(公告)号：US07772398B2
公开(公告)日：2010-08-10
申请号：US11079881
申请日：2005-03-11
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
摘要翻译： 提供氯吡格雷硫酸氢盐的结晶形式I的制备方法，其包括将氯吡格雷硫酸氢盐的结晶形式I从氯吡格雷游离碱的溶液分离在2-丙醇或2-丁醇的溶剂中。
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公开(公告)号：US20070225320A1
公开(公告)日：2007-09-27
申请号：US11691295
申请日：2007-03-26
IPC分类号： A61K31/4743 , C07D498/02
CPC分类号： C07D495/04
摘要： A process for preparing clopidogrel or a salt thereof.
摘要翻译： 氯吡格雷或其盐的制备方法。
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公开(公告)号：US20090149662A1
公开(公告)日：2009-06-11
申请号：US12328374
申请日：2008-12-04
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Sreenivasulu Kurella , Janardana Sarma Ramachandra Kopparapu , Rama Krishna Venkata Medisetti , Srinivasula Reddy Maddula
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Sreenivasulu Kurella , Janardana Sarma Ramachandra Kopparapu , Rama Krishna Venkata Medisetti , Srinivasula Reddy Maddula
IPC分类号： C07D209/18 , C07D403/06 , C07D403/12 , G01N21/00
CPC分类号： C07D209/18 , C07D403/06 , C07D403/12
摘要： An improved process for the preparation of substantially pure zafirlukast and pharmaceutical compositions thereof.
摘要翻译： 一种用于制备基本上纯的扎非司酮及其药物组合物的改进方法。
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4.发明申请PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS 审中-公开制备PIOGLITAZONE及其药物接受口服的方法公开(公告)号：US20090118514A1
公开(公告)日：2009-05-07
申请号：US12265142
申请日：2008-11-05
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Lokeswara Rao Madivada , Prabhakar Macharla , Kavitha Charagondla
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Lokeswara Rao Madivada , Prabhakar Macharla , Kavitha Charagondla
IPC分类号： C07D417/12
CPC分类号： C07D417/12
摘要： An improved process for the preparation of pioglitazone and its pharmaceutically acceptable salts by reducing 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzilidene]-2,4-thiazolidinedione with sodium borohydride in presence of a cobalt ion and dimethyl glyoxime. More particularly the cobalt ion used is cobalt chloride hexahydrate, or, cobalt (II) nitrate hexahydrate in presence of mixture of DMF and water as solvents.
摘要翻译： 一种通过在钴存在下还原5- [4- [2-（5-乙基-2-吡啶基）乙氧基]亚苄基] -2,4-噻唑烷二酮与硼氢化钠来制备吡格列酮及其药学上可接受的盐的改进方法 离子和二甲基乙二醛。 更具体地说，所用的钴离子是氯化钴六水合物，或硝酸钴（II）六水合物，在DMF和水的混合物存在下作为溶剂。
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公开(公告)号：US20110151258A1
公开(公告)日：2011-06-23
申请号：US13036520
申请日：2011-02-28
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Aalla , Lokeswara Rao Madivada , Prabhaker Macherla , Srinivas Kurella , Kavitha Charagondla , Ramamurthy Kasula , Rajagopala Rao Mandadapu , Krishaniah Charagondla , Malati Vakamulla , Durga Prasad Janaki Bhavanipurapu
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Aalla , Lokeswara Rao Madivada , Prabhaker Macherla , Srinivas Kurella , Kavitha Charagondla , Ramamurthy Kasula , Rajagopala Rao Mandadapu , Krishaniah Charagondla , Malati Vakamulla , Durga Prasad Janaki Bhavanipurapu
IPC分类号： B32B5/16 , C07D295/15
CPC分类号： C07D295/15 , Y10T428/2982
摘要： Preparation of ranolazine and intermediates thereof, for use in pharmaceutical compositions comprising ranolazine.
摘要翻译： 雷诺嗪及其中间体的制备，用于包含雷诺嗪的药物组合物中。
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公开(公告)号：US20130274284A1
公开(公告)日：2013-10-17
申请号：US13814596
申请日：2011-08-02
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Aalla , Dattatray Shamrao Metil , Srinivas Kurella , Kavitha Charagondla
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Aalla , Dattatray Shamrao Metil , Srinivas Kurella , Kavitha Charagondla
IPC分类号： C07D495/04
CPC分类号： C07D495/04 , A61K31/4365
摘要： The present application relates to process for the preparation of prasugrel, its pharmaceutically acceptable salts, and its intermediates.
摘要翻译： 本申请涉及制备普拉格雷及其药学上可接受的盐及其中间体的方法。
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公开(公告)号：US07919633B2
公开(公告)日：2011-04-05
申请号：US12051059
申请日：2008-03-19
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Thirupathi Reddy Akki , Yakambram Bojja
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Thirupathi Reddy Akki , Yakambram Bojja
IPC分类号： C07D231/12
CPC分类号： C07D231/12 , C07C311/39
摘要： There is provided a process for preparation of celecoxib by reacting 4,4,4-trifluoro-1-[4-(methyl)phenyl]butane-1,3-dione with 4-sulphonamidophenylhydrazine or its salt in a solvent medium that contains an alkyl ester. There is also provided a process for the purification of celecoxib using aromatic hydrocarbon solvents.
摘要翻译： 提供了一种通过使4,4,4-三氟-1- [4-（甲基）苯基]丁烷-1,3-二酮与4-磺酰胺基苯肼或其盐在含有 烷基酯。 还提供了使用芳烃溶剂来净化塞来昔布的方法。
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公开(公告)号：US20080234491A1
公开(公告)日：2008-09-25
申请号：US12051059
申请日：2008-03-19
申请人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Thirupathi Reddy Akki , Yakambram Bojja
发明人： Raghupathi Reddy Anumula , Goverdhan Gilla , Sampath Alla , Thirupathi Reddy Akki , Yakambram Bojja
IPC分类号： C07D231/14 , C07C243/10 , C07C311/16
CPC分类号： C07D231/12 , C07C311/39
摘要： There is provided a process for preparation of celecoxib by reacting 4,4,4-trifluoro-1-[4-(methyl)phenyl]butane-1,3-dione with 4-sulphonamidophenylhydrazine or its salt in a solvent medium that contains an alkyl ester. There is also provided a process for the purification of celecoxib using aromatic hydrocarbon solvents.
摘要翻译： 提供了一种通过使4,4,4-三氟-1- [4-（甲基）苯基]丁烷-1,3-二酮与4-磺酰胺基苯肼或其盐在含有 烷基酯。 还提供了使用芳烃溶剂来净化塞来昔布的方法。
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