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公开(公告)号:US08497085B2
公开(公告)日:2013-07-30
申请号:US13299067
申请日:2011-11-17
申请人: Georg Gübitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
发明人: Georg Gübitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
IPC分类号: C12Q1/04
CPC分类号: G01N21/78 , G01N33/528 , G01N33/6893 , G01N2333/908 , G01N2333/924 , G01N2333/96433 , G01N2333/966 , G01N2800/26
摘要: Described herein is a method for detecting a wound infection comprising the steps of: contacting a sample obtained from a wound with at least two substrates for at least two enzymes selected from the group consisting of lysozyme, elastase, cathepsin G and myeloperoxidase, and detecting a wound infection when a conversion of the at least two substrates with said at least two enzymes are determined.
摘要翻译: 本文描述了一种用于检测伤口感染的方法,包括以下步骤:将获自伤口的样品与至少两种底物接触,所述至少两种酶选自溶菌酶,弹性蛋白酶,组织蛋白酶G和髓过氧化物酶,并检测 当确定至少两种底物与所述至少两种酶的转化时,伤口感染。
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公开(公告)号:US20120258483A1
公开(公告)日:2012-10-11
申请号:US13299067
申请日:2011-11-17
申请人: Georg Gubitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
发明人: Georg Gubitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
IPC分类号: G01N21/78
CPC分类号: G01N21/78 , G01N33/528 , G01N33/6893 , G01N2333/908 , G01N2333/924 , G01N2333/96433 , G01N2333/966 , G01N2800/26
摘要: The present invention relates to a method for detecting a wound infection comprising the steps of: contacting a sample obtained from a wound with at least two substrates for at least two enzymes selected from the group consisting of lysozyme, elastase, cathepsin G and myeloperoxidase, and detecting a wound infection when a conversion of the at least two substrates with said at least two enzymes are determined.
摘要翻译: 本发明涉及一种检测伤口感染的方法,包括以下步骤:将获自伤口的样品与至少两种选自由溶菌酶,弹性蛋白酶,组织蛋白酶G和髓过氧化物酶组成的组中的至少两种底物接触,以及 当确定所述至少两种底物与所述至少两种酶的转化时,检测伤口感染。
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公开(公告)号:US08822173B2
公开(公告)日:2014-09-02
申请号:US13943009
申请日:2013-07-16
申请人: Eva Wehrschütz-Sigl
发明人: Georg Gubitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
IPC分类号: C12Q1/34
CPC分类号: G01N21/78 , G01N33/528 , G01N33/6893 , G01N2333/908 , G01N2333/924 , G01N2333/96433 , G01N2333/966 , G01N2800/26
摘要: The present invention relates to a wound dressing or a wound swab, which allows the detection of at least three enzymes selected from the group consisting of lysosyme, elastase, cathepsin G and myeloperoxidase using colored substrate agents for these enzymes. These enzyme substrates can be bound to medically acceptable polymers or fibers.
摘要翻译: 本发明涉及创伤敷料或伤口拭子,其允许使用用于这些酶的着色底物试剂检测至少三种选自溶酶体,弹性蛋白酶,组织蛋白酶G和髓过氧化物酶的酶。 这些酶底物可以结合到医学上可接受的聚合物或纤维上。
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公开(公告)号:US20130337484A1
公开(公告)日:2013-12-19
申请号:US13943009
申请日:2013-07-16
申请人: Eva Wehrschütz-Sigl
发明人: Georg Gubitz , Eva Wehrschütz-Sigl , Andrea Hasmann , Barbara Binder , Michael Burnett , Michael Schintler
IPC分类号: G01N21/78
CPC分类号: G01N21/78 , G01N33/528 , G01N33/6893 , G01N2333/908 , G01N2333/924 , G01N2333/96433 , G01N2333/966 , G01N2800/26
摘要: The present invention relates to a method for detecting a wound infection comprising the steps of: contacting a sample obtained from a wound with at least two substrates for at least two enzymes selected from the group consisting of lysozyme, elastase, cathepsin G and myeloperoxidase, and detecting a wound infection when a conversion of the at least two substrates with said at least two enzymes are determined.
摘要翻译: 本发明涉及一种检测伤口感染的方法,包括以下步骤:将获自伤口的样品与至少两种选自由溶菌酶,弹性蛋白酶,组织蛋白酶G和髓过氧化物酶组成的组中的至少两种底物接触,以及 当确定所述至少两种底物与所述至少两种酶的转化时,检测伤口感染。
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