公开(公告)号：US20240271176A1

公开(公告)日：2024-08-15

申请号：US18106252

申请日：2023-02-06

Applicant: Evolve Scientific Solutions LLC

Inventor： Thulasidharan Gandhi ,  Anthony Yesudass S

IPC: C12Q1/00 ,  G01N33/66

CPC classification number: C12Q1/004 ,  G01N33/66

Abstract: Organometallic redox mediator compounds, such as substituted ferrocenes or other metallocenes, and redox polymers comprising the organometallic redox mediators are described. The organic groups of the organometallic redox mediators can be substituted with multiple (e.g., at least three or at least four) electron-donating substituents, which can reduce the redox potential of the redox mediator compared to the corresponding unsubstituted redox mediator. Electrodes coated with the redox polymers or blends comprising the redox polymers are described, as are related electrochemical sensors. In addition, methods of using the sensors to detect biological analytes of interest, such as glucose or ketones, are described.

公开(公告)号：US20240053292A1

公开(公告)日：2024-02-15

申请号：US18236075

申请日：2023-08-21

Applicant: Evolve Scientific Solutions LLC

Inventor： Thulasidharan Gandhi ,  Anthony Yesudass S

IPC: G01N27/327 ,  C12Q1/00 ,  C12Q1/26 ,  G01N27/333 ,  C08F30/04 ,  C08L43/00 ,  C09D5/24 ,  C09D143/00

CPC classification number: G01N27/3277 ,  C12Q1/002 ,  C12Q1/005 ,  C12Q1/26 ,  G01N27/3335 ,  C08F30/04 ,  C08L43/00 ,  C09D5/24 ,  C09D143/00 ,  C08L2203/20 ,  A61B5/1486

Abstract: Organometallic redox mediator compounds, such as substituted ferrocenes or other metallocenes, and redox polymers comprising the organometallic redox mediators are described. The organic groups of the organometallic redox mediators can be substituted with multiple (e.g., at least three or at least four) electron-donating substituents, which can reduce the redox potential of the redox mediator compared to the corresponding unsubstituted redox mediator. Electrodes coated with the redox polymers or blends comprising the redox polymers are described, as are related electrochemical sensors. In addition, methods of using the sensors to detect biological analytes of interest, such as glucose or ketones, are described.