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公开(公告)号：US20110280922A1
公开(公告)日：2011-11-17
申请号：US13063887
申请日：2009-11-09
申请人： Eyal S. Ron , William F. Crowley , Robert Langer , Surajit K. Biswas , Quentin Baca , Armen Tashjian , Preston H. Saunders
发明人： Eyal S. Ron , William F. Crowley , Robert Langer , Surajit K. Biswas , Quentin Baca , Armen Tashjian , Preston H. Saunders
IPC分类号： A61F13/20 , A61K38/02 , A61P31/12 , A61K47/32 , A61K47/34 , A61M31/00 , A61K31/56 , A61K38/09
CPC分类号： A61K47/32 , A61F13/20 , A61K9/0036 , A61K9/0092 , A61K38/09 , A61M31/002
摘要： The invention relates to a therapeutic device for the delivery of therapeutic agents, e.g. a peptide such as leuprolide, via the vagina to a female mammal. In some embodiments, the invention also relates to methods for the treatment of obesity and eating disorders, diabetes, multiple sclerosis (MS), endometriosis, uterine fibroids, polycystic ovarian disease, various cancers such as breast cancer, acne, hirsutism, microbial or fungal or viral infections such as bacterial vaginosis or AIDS/HIV, and chronic diseases using a disclosed vaginal device.
摘要翻译： 本发明涉及用于递送治疗剂的治疗装置，例如， 一种肽，如亮丙瑞林，通过阴道到雌性哺乳动物。 在一些实施方案中，本发明还涉及治疗肥胖症和进食障碍，糖尿病，多发性硬化（MS），子宫内膜异位症，子宫肌瘤，多囊卵巢疾病，各种癌症如乳腺癌，痤疮，多毛症，微生物或真菌的方法 或病毒感染如细菌性阴道炎或AIDS / HIV，以及使用公开的阴道装置的慢性疾病。
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公开(公告)号：US20080248017A1
公开(公告)日：2008-10-09
申请号：US12125571
申请日：2008-05-22
IPC分类号： A61K38/43 , A61K47/30 , A61K47/32 , A61K38/45 , A61K31/715 , A61K39/00 , A61K38/18 , A61K39/395 , A61K38/46 , A61K38/44 , A61K31/56
CPC分类号： A61F6/08 , A61F6/142 , A61K9/0036 , A61K9/0056 , A61K31/565 , A61K31/57 , A61K38/09 , A61K45/06 , Y10S514/843 , A61K2300/00
摘要： The invention relates to an drug delivery device and a method for delivering multiple drugs over a prolonged period of time. The drug delivery device has two or more unitary segments comprising a drug-permeable polymeric substance, wherein at least one of the segments further comprises a pharmaceutically active agent. The invention also relates to a method for the treatment of a benign ovarian secretory disorder in a female mammal, a method of contraception, and a method of relieving the symptoms associated with menopausal, perimenopausal and post-menopausal periods in a woman.
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公开(公告)号：US5824637A
公开(公告)日：1998-10-20
申请号：US807713
申请日：1997-02-28
IPC分类号： A61K38/00 , C07K14/575 , A61K38/03 , A61K38/16 , A61K38/17
CPC分类号： C07K14/575 , A61K38/00 , Y10S514/841 , Y10S514/843
摘要： A method for contraception which features administering to a patient a contraceptive agent having activin-antagonist activity. The contraceptive agent results in inhibition of the activin-stimulated release of FSH, thereby resulting in a decrease in fertility and facilitating contraception in the patient.
摘要翻译： 一种避孕方法，其特征在于向患者施用具有激活素拮抗剂活性的避孕药。 避孕药导致FSH的激活素刺激释放的抑制，从而导致生育力下降并促进患者的避孕。
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公开(公告)号：US5658876A
公开(公告)日：1997-08-19
申请号：US234261
申请日：1994-04-28
IPC分类号： A61K38/00 , C07K14/575 , A61K38/03 , A61K38/16 , A61K38/17
CPC分类号： C07K14/575 , A61K38/00 , Y10S514/841 , Y10S514/843
摘要： A method for contraception which features administering to a patient a contraceptive agent having activin-antagonist activity. The contraceptive agent results in inhibition of the activin-stimulated release of FSH, thereby resulting in a decrease in fertility and facilitating contraception in the patient.
摘要翻译： 一种避孕方法，其特征在于向患者施用具有激活素拮抗剂活性的避孕药。 避孕药导致FSH的激活素刺激释放的抑制，从而导致生育力下降并促进患者的避孕。
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