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公开(公告)号：US20220073950A1
公开(公告)日：2022-03-10
申请号：US17413297
申请日：2019-12-12
发明人： Erica Gabrielle Weinstein , Avak Kahvejian , Simon Delagrave , Nathan Lawrence Yozwiak , Kevin James Lebo , Fernando Martin Diaz , Dhananjay Maniklal Nawandar , Ryan D. Tedstone , Jared David Pitts
摘要： This invention relates generally to anellosomes and compositions and uses thereof.
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2.发明公开公开(公告)号：US20240327867A1
公开(公告)日：2024-10-03
申请号：US18605384
申请日：2024-03-14
发明人： Joseph Michael Cabral , Cato Hawkins Prince , Bryan Alexander McGuffie , Hassana Kia Oyibo , Simon Delagrave , Dhananjay Maniklal Nawandar , Kevin James Lebo , Cesar Augusto Arze , Agamoni Bhattacharyya , Nathan Lawrence Yozwiak , Roger Joseph Hajjar , Geoffrey Parsons
IPC分类号： C12N15/86 , A61K47/64 , C07K14/005
CPC分类号： C12N15/86 , A61K47/64 , C07K14/005 , C12N2750/00022 , C12N2750/00023 , C12N2750/00043 , C12N2750/00051 , C12N2750/00071 , C12N2830/008 , C12N2840/203
摘要： This invention relates generally to modified anellovirus capsid proteins, anellovectors, anelloVLPs, and compositions and uses thereof.
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公开(公告)号：US20220362315A1
公开(公告)日：2022-11-17
申请号：US17845660
申请日：2022-06-21
发明人： Simon Delagrave , Fernando Martin Diaz , Avak Kahvejian , Kevin James Lebo , Dhananjay Maniklal Nawandar , Jared David Pitts , Ryan D. Tedstone , Erica Gabrielle Weinstein , Nathan Lawrence Yozwiak
IPC分类号： A61K35/76 , C12N15/113 , C12N7/00 , C12N15/86
摘要： This invention relates generally to viral vectors and viral particles based on Anelloviruses, which can be used to deliver an agent (e.g., an exogenous effector or an endogenous effector, e.g., a therapeutic effector) to a cell (e.g., a cell in a subject to be treated therapeutically). Described herein are anellosomes, anellovectors, and compositions and uses thereof.
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公开(公告)号：US11446344B1
公开(公告)日：2022-09-20
申请号：US17489652
申请日：2021-09-29
发明人： Simon Delagrave , Fernando Martin Diaz , Avak Kahvejian , Kevin James Lebo , Dhananjay Maniklal Nawandar , Jared David Pitts , Ryan D. Tedstone , Erica Gabrielle Weinstein , Nathan Lawrence Yozwiak
IPC分类号： A61K35/76 , A61K48/00 , C12N15/86 , C12N7/00 , C12N15/113
摘要： This invention relates generally to viral vectors and viral particles based on Anelloviruses, which can be used to deliver an agent (e.g., an exogenous effector or an endogenous effector, e.g., a therapeutic effector) to a cell (e.g., a cell in a subject to be treated therapeutically). Described herein are anellosomes, anellovectors, and compositions and uses thereof.
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公开(公告)号：US11166996B2
公开(公告)日：2021-11-09
申请号：US16448589
申请日：2019-06-21
发明人： Erica Gabrielle Weinstein , Avak Kahvejian , Simon Delagrave , Nathan Lawrence Yozwiak , Kevin James Lebo , Fernando Martin Diaz , Dhananjay Maniklal Nawandar , Ryan D. Tedstone , Jared David Pitts
IPC分类号： C12N15/86 , A61K48/00 , A61K35/76 , C12N7/00 , C12N15/113
摘要： This invention relates generally to viral vectors and viral particles based on Anelloviruses, which can be used to deliver an agent (e.g., an exogenous effector or an endogenous effector, e.g., a therapeutic effector) to a cell (e.g., a cell in a subject to be treated therapeutically). Described herein are anellosomes, anellovectors, and compositions and uses thereof.
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公开(公告)号：US20230048858A1
公开(公告)日：2023-02-16
申请号：US17413207
申请日：2019-12-12
发明人： Erica Gabrielle Weinstein , Avak Kahvejian , Simon Delagrave , Nathan Lawrence Yozwiak , Kevin James Lebo , Fernando Martin Diaz , Dhananjay Maniklal Nawandar , Ryan D. Tedstone , Jared David Pitts
摘要： This invention relates generally to anellosomes and compositions and uses thereof.
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公开(公告)号：US20190211361A1
公开(公告)日：2019-07-11
申请号：US16366571
申请日：2019-03-27
发明人： Avak Kahvejian , Erica Gabrielle Weinstein , Nicholas McCartney Plugis , Kevin James Lebo , Fernando Martin Diaz , Dhananjay Maniklal Nawandar
IPC分类号： C12N15/86 , C12N15/113 , C07K14/005
CPC分类号： C12N15/86 , C07K14/005 , C12N15/113 , C12N2310/141 , C12N2320/32 , C12N2750/00021 , C12N2750/00022 , C12N2750/00043
摘要： This invention relates generally to pharmaceutical compositions and preparations of curons and uses thereof.
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公开(公告)号：US20240123083A1
公开(公告)日：2024-04-18
申请号：US18264320
申请日：2022-02-07
发明人： Simon Delagrave , Kevin James Lebo , Michael James DiBiasio-White , Dhananjay Maniklal Nawandar
IPC分类号： A61K48/00 , C07K14/005 , C12N7/00 , C12N15/86
CPC分类号： A61K48/0008 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2750/00022 , C12N2750/00044 , C12N2750/14122 , C12N2750/14143 , C12N2750/14144
摘要： This invention relates generally to compositions for making and administering anellovectors and uses thereof.
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公开(公告)号：US20230348933A1
公开(公告)日：2023-11-02
申请号：US18009557
申请日：2021-06-11
CPC分类号： C12N15/86 , A61K48/0041 , C12N2750/00021 , C12N2750/00043 , C12N2750/00051 , C12N2750/00071
摘要： This invention relates generally to compositions for making anellovectors and uses thereof. For instance, a method herein can comprise providing a nucleic acid construct that comprises a first Anellovirus genome encoding an exogenous effector and a second Anellovirus genome or fragment thereof, arranged in tandem. In some embodiments, the nucleic acid construct results in production of an anellovector comprising an Anellovirus genetic element encoding the exogenous effector, enclosed in a proteinaceous exterior.
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公开(公告)号：US20230279423A1
公开(公告)日：2023-09-07
申请号：US17812896
申请日：2022-07-15
发明人： Avak Kahvejian , Erica Gabrielle Weinstein , Nicholas McCartney Plugis , Kevin James Lebo , Fernando Martin Diaz , Dhananjay Maniklal Nawandar
IPC分类号： C12N15/86 , C12N7/00 , C12N15/113 , C07K14/005
CPC分类号： C12N15/86 , C12N7/00 , C12N15/1136 , C07K14/005 , C12N15/113 , C12N2750/00022 , C12N2750/00043 , C12N2750/00021 , C12N2310/141 , C12N2320/32
摘要： This invention relates generally to pharmaceutical compositions and preparations of curons and uses thereof.
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