公开(公告)号：US20150292008A1

公开(公告)日：2015-10-15

申请号：US14663010

申请日：2015-03-19

Applicant: FLUIDIGM CORPORATION

Inventor： Stanley N. Lapidus ,  PHILIP R. BUZBY ,  TIMOTHY D. HARRIS

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C12Q1/6869 ,  C12Q2527/113

Abstract: The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.

Abstract translation: 本发明提供了用于测序多核苷酸的方法，包括在反应已经运行到接近或完全完成之前通过合成反应在序列中停止延伸循环。

公开(公告)号：US20170096713A1

公开(公告)日：2017-04-06

申请号：US15266787

申请日：2016-09-15

Applicant: California Institute of Technology ,  Fluidigm Corporation

Inventor： Stanley N. Lapidus ,  Stephen R. Quake

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q1/6869 ,  C12Q2600/156

Abstract: The invention provides methods for determining the presence of a disease by comparing a sequence from a single target molecule with a predetermined sequence that is associated with a specific disease.

公开(公告)号：US20160362741A1

公开(公告)日：2016-12-15

申请号：US15013915

申请日：2016-02-02

Applicant: Fluidigm Corporation

Inventor： Stanley N. Lapidus

IPC: C12Q1/68

CPC classification number: C12Q1/68 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2565/518 ,  C12Q2563/107 ,  C12Q2533/101

Abstract: The invention provides methods and devices for detecting, enumerating or identifying target nucleic acid molecules using immobilized capture probes and single molecule sequencing techniques.

Abstract translation: 本发明提供了使用固定的捕获探针和单分子测序技术来检测，列举或鉴定靶核酸分子的方法和装置。

公开(公告)号：US09868978B2

公开(公告)日：2018-01-16

申请号：US15013915

申请日：2016-02-02

Applicant: Fluidigm Corporation

Inventor： Stanley N. Lapidus

IPC: C12Q1/68

CPC classification number: C12Q1/68 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2565/518 ,  C12Q2563/107 ,  C12Q2533/101

Abstract: The invention provides methods and devices for detecting, enumerating or identifying target nucleic acid molecules using immobilized capture probes and single molecule sequencing techniques.

公开(公告)号：US09657344B2

公开(公告)日：2017-05-23

申请号：US14663010

申请日：2015-03-19

Applicant: FLUIDIGM CORPORATION

Inventor： Stanley N. Lapidus ,  Philip R. Buzby ,  Timothy D. Harris

IPC: C12Q1/68 ,  C07H21/00

CPC classification number: C12Q1/6874 ,  C12Q1/6869 ,  C12Q2527/113

Abstract: The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.

公开(公告)号：US09284605B2

公开(公告)日：2016-03-15

申请号：US14318104

申请日：2014-06-27

Applicant: Fluidigm Corporation

Inventor： Stanley N. Lapidus

IPC: C12Q1/68

CPC classification number: C12Q1/68 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2565/518 ,  C12Q2563/107 ,  C12Q2533/101

Abstract: The invention provides methods and devices for detecting, enumerating or identifying target nucleic acid molecules using immobilized capture probes and single molecule sequencing techniques.

Abstract translation: 本发明提供了使用固定的捕获探针和单分子测序技术来检测，列举或鉴定靶核酸分子的方法和装置。