公开(公告)号：US20220213089A1

公开(公告)日：2022-07-07

申请号：US17439646

申请日：2020-03-13

申请人： FORMA Therapeutics, Inc.

发明人： Shawn E.R. SCHILLER ,  Torsten HERBERTZ ,  Hongbin LI ,  Bradford GRAVES ,  Steven MISCHKE ,  Angela V. WEST ,  Anna ERICSSON ,  Jennifer R. DOWNING

IPC分类号： C07D471/04

摘要： The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains (e.g., certain forms of cancer), and methods of synthesis of these compounds.