公开(公告)号：US11254674B2

公开(公告)日：2022-02-22

申请号：US16946159

申请日：2020-06-08

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E. R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20220169647A1

公开(公告)日：2022-06-02

申请号：US17669135

申请日：2022-02-10

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela V. West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04 ,  A61P35/00 ,  C07D519/00

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20200299295A1

公开(公告)日：2020-09-24

申请号：US16946159

申请日：2020-06-08

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20240150349A1

公开(公告)日：2024-05-09

申请号：US18463587

申请日：2023-09-08

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela V. West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04 ,  A61P35/00 ,  C07D519/00

CPC classification number: C07D471/04 ,  A61P35/00 ,  C07D519/00

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US11787803B2

公开(公告)日：2023-10-17

申请号：US17669135

申请日：2022-02-10

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E. R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela V. West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04 ,  C07D519/00 ,  A61P35/00

CPC classification number: C07D471/04 ,  A61P35/00 ,  C07D519/00

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20200216445A1

公开(公告)日：2020-07-09

申请号：US16647478

申请日：2018-09-14

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela V. West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04 ,  C07D519/00 ,  A61P35/00

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20220162207A1

公开(公告)日：2022-05-26

申请号：US17669112

申请日：2022-02-10

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US11292791B2

公开(公告)日：2022-04-05

申请号：US16647478

申请日：2018-09-14

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E. R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela V. West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04 ,  C07D519/00 ,  A61P35/00

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

公开(公告)号：US20200002332A1

公开(公告)日：2020-01-02

申请号：US16457596

申请日：2019-06-28

Applicant: FORMA Therapeutics, Inc.

Inventor： Shawn E.R. Schiller ,  Torsten Herbertz ,  Hongbin Li ,  Bradford Graves ,  Steven Mischke ,  Angela West ,  Jennifer R. Downing ,  Anna Ericsson

IPC: C07D471/04

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.