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公开(公告)号:US20240132499A1
公开(公告)日:2024-04-25
申请号:US18476249
申请日:2023-09-27
Applicant: FORMA Therapeutics, Inc.
Inventor: Alex J. Buckmelter , Justin Andrew Caravella , Hongbin Li , Matthew W. Martin , Steven Mischke , David James Richard , Angela V. West
IPC: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
CPC classification number: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.
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公开(公告)号:US11292791B2
公开(公告)日:2022-04-05
申请号:US16647478
申请日:2018-09-14
Applicant: FORMA Therapeutics, Inc.
Inventor: Shawn E. R. Schiller , Torsten Herbertz , Hongbin Li , Bradford Graves , Steven Mischke , Angela V. West , Jennifer R. Downing , Anna Ericsson
IPC: C07D471/04 , C07D519/00 , A61P35/00
Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
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公开(公告)号:US20240150349A1
公开(公告)日:2024-05-09
申请号:US18463587
申请日:2023-09-08
Applicant: FORMA Therapeutics, Inc.
Inventor: Shawn E.R. Schiller , Torsten Herbertz , Hongbin Li , Bradford Graves , Steven Mischke , Angela V. West , Jennifer R. Downing , Anna Ericsson
IPC: C07D471/04 , A61P35/00 , C07D519/00
CPC classification number: C07D471/04 , A61P35/00 , C07D519/00
Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
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公开(公告)号:US11787803B2
公开(公告)日:2023-10-17
申请号:US17669135
申请日:2022-02-10
Applicant: FORMA Therapeutics, Inc.
Inventor: Shawn E. R. Schiller , Torsten Herbertz , Hongbin Li , Bradford Graves , Steven Mischke , Angela V. West , Jennifer R. Downing , Anna Ericsson
IPC: C07D471/04 , C07D519/00 , A61P35/00
CPC classification number: C07D471/04 , A61P35/00 , C07D519/00
Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
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公开(公告)号:US20210355126A1
公开(公告)日:2021-11-18
申请号:US17282521
申请日:2019-10-04
Applicant: FORMA Therapeutics, Inc.
Inventor: Alex J. Buckmelter , Justin Andrew Caravella , Hongbin Li , Matthew W. Martin , Steven Mischke , David James Richard , Angela V. West
IPC: C07D471/18 , C07D471/08 , C07D487/18 , C07D403/12 , C07D487/08 , C07D491/107
Abstract: The disclosure relates to USP30 Inhibitor Compounds I, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same. (I)
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公开(公告)号:US20200216445A1
公开(公告)日:2020-07-09
申请号:US16647478
申请日:2018-09-14
Applicant: FORMA Therapeutics, Inc.
Inventor: Shawn E.R. Schiller , Torsten Herbertz , Hongbin Li , Bradford Graves , Steven Mischke , Angela V. West , Jennifer R. Downing , Anna Ericsson
IPC: C07D471/04 , C07D519/00 , A61P35/00
Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
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公开(公告)号:US11814386B2
公开(公告)日:2023-11-14
申请号:US18048079
申请日:2022-10-20
Applicant: FORMA Therapeutics, Inc.
Inventor: Alex J. Buckmelter , Justin Andrew Caravella , Hongbin Li , Matthew W. Martin , Steven Mischke , David James Richard , Angela V. West
IPC: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
CPC classification number: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.
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公开(公告)号:US20230126252A1
公开(公告)日:2023-04-27
申请号:US18048079
申请日:2022-10-20
Applicant: FORMA Therapeutics, Inc.
Inventor: Alex J. Buckmelter , Justin Andrew Caravella , Hongbin Li , Matthew W. Martin , Steven Mischke , David James Richard , Angela V. West
IPC: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.
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公开(公告)号:US11535618B2
公开(公告)日:2022-12-27
申请号:US17282521
申请日:2019-10-04
Applicant: FORMA Therapeutics, Inc.
Inventor: Alex J. Buckmelter , Justin Andrew Caravella , Hongbin Li , Matthew W. Martin , Steven Mischke , David James Richard , Angela V. West
IPC: C07D471/18 , C07D403/12 , C07D471/08 , C07D487/08 , C07D487/18 , C07D491/107
Abstract: The disclosure relates to USP30 Inhibitor Compounds I, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same. (I)
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公开(公告)号:US20220169647A1
公开(公告)日:2022-06-02
申请号:US17669135
申请日:2022-02-10
Applicant: FORMA Therapeutics, Inc.
Inventor: Shawn E.R. Schiller , Torsten Herbertz , Hongbin Li , Bradford Graves , Steven Mischke , Angela V. West , Jennifer R. Downing , Anna Ericsson
IPC: C07D471/04 , A61P35/00 , C07D519/00
Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
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