公开(公告)号：US11041090B2

公开(公告)日：2021-06-22

申请号：US16314630

申请日：2017-06-30

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Rainer Haag ,  Marie Weinhart ,  Qiang Wei ,  Leixiao Yu

IPC: C09D171/02 ,  C12M1/00 ,  C08G83/00 ,  C09D201/00 ,  C08G65/00 ,  C09D201/06 ,  C09D201/02 ,  C08G65/22 ,  C08G65/334 ,  C09D5/00

Abstract: The disclosure relates to an amphiphilic block copolymer comprising a first block consisting of a polymeric hydrophilic domain, wherein the polymeric hydrophilic domain consists of a polyglycerol; an optional second block consisting of a hydrophobic domain and a first linker domain, wherein the second block is covalently bound to the first block via the first linker domain, an optional third block consisting of a catechol domain and a second linker domain, wherein the third block is covalently bound to the first block via the second linker domain; and a fourth block consisting of a crosslinking domain and a third linker domain, wherein the fourth block is covalently bound to the first block via the third linker domain, wherein the crosslinking domain comprises a reactive residue enabling a crosslinking between individual molecules of the amphiphilic block copolymer.

公开(公告)号：US10047230B2

公开(公告)日：2018-08-14

申请号：US15021250

申请日：2014-09-08

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Rainer Haag ,  Marie Weinhart ,  Qiang Wei ,  Tobias Becherer ,  Ingo Grunwald

IPC: A61F2/02 ,  C09D5/16 ,  C08G83/00 ,  A61L27/34 ,  C08J7/04 ,  C09D201/00 ,  C09D201/06 ,  C08L101/00 ,  C12M1/00 ,  A61F2/00 ,  C09D171/00

Abstract: An article, comprising a substrate and a polymer film attached to the substrate is provided, the polymer film comprising a first layer of a first polymer functionalized by a first functionalization compound covalently bound to said first polymer and bearing at least one catecholic group being present on a surface of the first layer. The polymer film is a layered film, a top layer of which is formed by the first layer, the layered film comprising at least one further layer of at least one further polymer functionalized by a further functionalization compound covalently bound to said further polymer and bearing at least one catecholic group being present on a surface of the at least one further layer, wherein an average ratio of catecholic groups per polymer molecule is equal to or less than 1 in case of the first polymer and greater than 1 in case of the further polymer.