公开(公告)号：US20190314335A1

公开(公告)日：2019-10-17

申请号：US16448069

申请日：2019-06-21

Applicant: FUJIFILM Corporation

Inventor： Yuta YOSHINO ,  Hayato OGURA ,  Mikinaga MORI ,  Taisuke ENDO ,  Kentaro NUMAJIRI ,  Ritsuko HORI

IPC: A61K31/4045 ,  A61K9/127 ,  A61K35/00

Abstract: An object of the present invention is to provide a lipid particle composition containing panobinostat or a salt thereof and exhibiting a high bone marrow-targeting capability, and a pharmaceutical composition including the lipid particle composition. According to the present invention, provided is a lipid particle composition containing panobinostat or a salt thereof, in which a lipid particle contains a phospholipid and cholesterol.

公开(公告)号：US20160355662A1

公开(公告)日：2016-12-08

申请号：US15238723

申请日：2016-08-17

Applicant: FUJIFILM CORPORATION

Inventor： Shinsuke TOKUOKA ,  Ritsuko HORI

IPC: C08J9/28 ,  C08B16/00 ,  C08B1/00

CPC classification number: C08J9/28 ,  C08B1/003 ,  C08B15/10 ,  C08B16/00 ,  C08J2201/0546 ,  C08J2301/00 ,  C08J2301/02

Abstract: Provided are a method of manufacturing porous cellulose particles, including a cellulose solution preparation step of preparing a cellulose solution by dissolving cellulose in an aqueous lithium bromide solution, a dispersion preparation step of preparing a cellulose solution dispersion by dispersing the cellulose solution in an organic dispersion medium, and a coagulation step of coagulating cellulose in the cellulose solution dispersion by cooling the cellulose solution dispersion and adding a coagulation solvent thereto such that porous particles are obtained, and porous cellulose particles obtained by the method for manufacturing porous cellulose particles.

Abstract translation: 提供一种制造多孔纤维素颗粒的方法，包括通过将纤维素溶解在溴化锂水溶液中制备纤维素溶液的纤维素溶液制备步骤，通过将纤维素溶液分散在有机分散体中制备纤维素溶液分散体的分散体制备步骤 介质和凝固步骤，通过冷却纤维素溶液分散体并在其中加入凝固溶剂使得得到多孔颗粒，以及通过制造多孔纤维素颗粒的方法获得的多孔纤维素颗粒，将纤维素凝结在纤维素溶液分散体中。