公开(公告)号：US20240018547A1

公开(公告)日：2024-01-18

申请号：US18448499

申请日：2023-08-11

Applicant: FUJIFILM Corporation

Inventor： Yusuke Mori ,  Taichi MURAGUCHI ,  Sayako UMETANI ,  Yuya WATANABE

IPC: C12N15/86 ,  C12N7/02

CPC classification number: C12N15/86 ,  C12N7/02 ,  C12N2750/14143

Abstract: An object of the present invention is to provide a kit and an integration vector for preparing an adeno-associated virus-producing cell capable of controlled manufacture of an adeno-associated virus, and to provide an adeno-associated virus-producing cell capable of controlled manufacture of an adeno-associated virus, a manufacturing method of the same, and a manufacturing method of the adeno-associated virus. According to the present invention, a kit including a first vector containing one or more virus helper genes, in which at least one of the virus helper genes is under a control of a promoter capable of regulating expression, and a second vector containing one or more adeno-associated virus genes, in which at least one of the adeno-associated virus genes is not under a control of a promoter regulating expression is provided.