公开(公告)号：US20240008514A1

公开(公告)日：2024-01-11

申请号：US17857937

申请日：2022-07-05

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Simon Lykke Roest Laursen ,  Sanne Skov Jensen

IPC: A23L29/00 ,  A61K36/185 ,  A23L29/30 ,  A23L33/105 ,  A23L27/30

CPC classification number: A23L29/035 ,  A61K36/185 ,  A23L29/37 ,  A23L33/105 ,  A23L27/34

Abstract: The invention relates to a powder premixture for oral administration of cannabinoids, comprising a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture; a lipid composition comprising one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and a sweetener powder composition comprising one or more sweeteners, wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4.

公开(公告)号：US20240316077A1

公开(公告)日：2024-09-26

申请号：US18612067

申请日：2024-03-21

Applicant: Fertin Pharma A/S

Inventor： Sanne Skov Jensen ,  Gitte Nykjær Nikolajsen ,  Simon Laursen ,  Dorthe Schackinger Boesen

IPC: A61K31/00 ,  A61K9/00 ,  A61K47/02 ,  A61K47/10 ,  A61K47/14 ,  A61K47/44

CPC classification number: A61K31/658 ,  A61K9/0056 ,  A61K36/3482 ,  A61K47/02 ,  A61K47/10 ,  A61K47/14 ,  A61K47/44

Abstract: An orally dissolvable or chewable tableted powder formulation is presented. The formulation includes one or more carrier systems including one or more liquid or solid self-emulsifying systems loaded with cannabinoids in an amount of at least 10% by weight of the tableted powder formulation. The one or more self-emulsifying systems includes: at least one or more surfactants, one or more lipids and one or more isolated or synthetic cannabinoids when self-emulsifying system is a liquid self-emulsifying system, and at least one or more surfactants, one or more waxes and one or more isolated or synthetic cannabinoids when self-emulsifying system is a solid self-emulsifying system. The formulation further includes one or more water-soluble agents in an amount of 20-80% by weight of the tableted powder formulation and one or more flavors. The one or more surfactants includes one or more surfactants having a chemical structure that includes a polyethylene glycol moiety.

公开(公告)号：US20250009767A1

公开(公告)日：2025-01-09

申请号：US18765566

申请日：2024-07-08

Applicant: Fertin Pharma A/S

Inventor： Helle Wittorff ,  Sanne Skov Jensen ,  Gitte Nykjær Nikolajsen ,  Gordon Findlay Dawson

IPC: A61K31/00 ,  A61K9/00 ,  A61K9/20 ,  A61K45/06

Abstract: An adhesive oral disc for sustained release of cannabinoids is presented. The disc includes one or more cannabinoids and is composed of at least a mucosal contacting layer having a mucosal contacting surface operable to be fixed to the gingiva of a person in need of alleviation or treatment of a medical condition, where the mucosal contacting layer includes one or more mucoadhesive polymers allowing the adhesive oral disc to adhere to the gingiva for an extended period of time. Further, the disc includes a non-mucoadhesive module fused to the mucosal contacting layer, where the non-mucoadhesive module includes a solid tablet composition allowing the non-mucoadhesive module to dissolve within an extended period of time upon adhesion of the adhesive oral disc to the gingiva. The invention is particularly useful for alleviation or treatment of ulcers.

公开(公告)号：US20240415853A1

公开(公告)日：2024-12-19

申请号：US18612256

申请日：2024-03-21

Applicant: Fertin Pharma A/S

Inventor： Sanne Skov Jensen ,  Gitte Nykjær Nikolajsen ,  Simon Laursen ,  Dorthe Schackinger Boesen

IPC: A61K31/00 ,  A61K9/00 ,  A61K9/48 ,  A61K47/02 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44

Abstract: An orally dissolvable or chewable tableted powder formulation is presented. The formulation includes one or more carrier systems including one or more liquid or solid self-emulsifying systems loaded with cannabinoids in an amount of at least 10% by weight of the tableted powder formulation. The one or more self-emulsifying systems includes: at least one or more surfactants, one or more lipids and one or more isolated or synthetic cannabinoids when the self-emulsifying system is a liquid self-emulsifying system, and at least one or more surfactants, one or more waxes and one or more isolated or synthetic cannabinoids when the self-emulsifying system is a solid self-emulsifying system. The formulation further includes one or more water-soluble agents in an amount of 20-80% by weight of the tableted powder formulation and one or more flavors.

公开(公告)号：US20240350404A1

公开(公告)日：2024-10-24

申请号：US18612007

申请日：2024-03-21

Applicant: Fertin Pharma A/S

Inventor： Sanne Skov Jensen ,  Gitte Nykjær Nikolajsen ,  Simon Laursen ,  Dorthe Schackinger Boesen

IPC: A61K9/00 ,  A61K31/00

CPC classification number: A61K9/0056 ,  A61K31/658

Abstract: An orally dissolvable or chewable tableted powder formulation, includes one or more mesoporous silica carriers loaded with a liquid cannabinoid suspension or solution; one or more water-soluble agents in an amount of 20-80% by weight of the tableted powder formulation; and one or more flavors, wherein the liquid cannabinoid suspension or solution includes one or more cannabinoids and one or more non-volatile solvents in a weight ratio of cannabinoid to solvent of 10:1 to 1:10.