公开(公告)号：US20240218414A1

公开(公告)日：2024-07-04

申请号：US17291967

申请日：2019-11-01

申请人： Firmenich Incorporated

发明人： Andrew P. Patron ,  Chris Edano Noriega ,  Rama Rao Manam ,  Justin Colquitt ,  Nathan Faber ,  Helge Zieler ,  Justin Stege

IPC分类号： C12P33/20 ,  C12N9/02 ,  C12N9/10 ,  C12N9/90 ,  C12N15/52 ,  C12N15/63

CPC分类号： C12P33/20 ,  C12N9/0071 ,  C12N9/1051 ,  C12N9/90 ,  C12N15/52 ,  C12N15/63 ,  C12Y204/01017 ,  C12Y504/99033

摘要： Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example host cells) for making the mogroside compounds, and the mogroside compounds made by the methods disclosed herein, and compositions (for example, cell lysates) and recombinant cells comprising the mogroside compounds (e.g., Compound 1). Also provided herein are novel cucurbitadienol synthases and the use thereof.

公开(公告)号：US20240240222A1

公开(公告)日：2024-07-18

申请号：US18562801

申请日：2022-06-27

申请人： Firmenich Incorporated

发明人： Chris Edano Noriega ,  Rama Rao Manam ,  Andrew P. Patron

IPC分类号： C12P33/20 ,  C12N9/10 ,  C12N9/24 ,  C12N15/66

CPC分类号： C12P33/20 ,  C12N9/1051 ,  C12N9/2402 ,  C12N15/66

摘要： Provided herein include methods of making mogroside compounds. e.g., siamenoside I 1, compositions (for example host cells) for making the mogroside compounds, and the mogroside compounds made by the methods disclosed herein, and compositions (for example, cell lysates) and recombinant cells comprising the mogroside compounds (e.g., siamenoside I). Also provided herein are novel cucurbitadienol synthases and the use thereof.

公开(公告)号：US20210388021A1

公开(公告)日：2021-12-16

申请号：US17291814

申请日：2020-04-01

申请人： Firmenich Incorporated

发明人： Rama Rao Manam ,  Nicole Servant ,  Andrew P. Patron ,  Christina Susanto ,  Emilia Avanes

IPC分类号： C07J17/00 ,  A23L27/30

摘要： The present invention includes compounds having structural formula (I), wherein R1-R9 are as defined herein, or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of compositions.

公开(公告)号：US20240218402A1

公开(公告)日：2024-07-04

申请号：US17291945

申请日：2019-11-01

申请人： Firmenich Incorporated

发明人： Andrew P. Patron ,  Chris Edano Noriega ,  Rama Rao Manam ,  Justin Colquitt ,  Nathan Faber ,  Helge Zieler ,  Justin Stege ,  Daniel K. Olson

IPC分类号： C12P7/22 ,  C12N9/10 ,  C12N9/26 ,  C12N9/42 ,  C12N15/52

CPC分类号： C12P7/22 ,  C12N9/1051 ,  C12N9/1074 ,  C12N9/2411 ,  C12N9/2437 ,  C12N15/52 ,  C12Y204/01005 ,  C12Y204/01019 ,  C12Y302/01004

摘要： Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example, host cells) for making mogroside compounds, and the mogroside compounds made by the methods and compositions disclosed herein, compositions made by the methods (for example, cell lysates), and recombinant cells comprising the mogroside compounds (e.g., Compound 1).