公开(公告)号：US20180208948A1

公开(公告)日：2018-07-26

申请号：US15330813

申请日：2015-05-06

Applicant: Firmenich SA

Inventor： Laurent DAVIET ,  Olivier HAEFLIGER ,  Xiu-Feng HE ,  Jian LI ,  Yu-Hua ZHANG

IPC: C12P7/02 ,  C12N9/88

CPC classification number: C12P7/02 ,  C12N9/88 ,  C12Y402/03

Abstract: The present invention relates to a method of producing drimenol and/or drimenol derivatives by contacting at least one polypeptide with farnesyl diphosphate. The method may be performed in vitro or in vivo. The present invention also provides amino acid sequences of polypeptides useful in the method of the invention and nucleic acid encoding the polypeptides of the invention. The method further provides host cells or organisms genetically modified to express the polypeptides of the invention and useful to produce drimenol and/or drimenol derivatives.