公开(公告)号：US10689609B2

公开(公告)日：2020-06-23

申请号：US15634955

申请日：2017-06-27

申请人： FloDesign Sonics, Inc.

发明人： Thomas J. Kennedy, III ,  Bart Lipkens ,  Stanley J. Kowalski, III ,  Anthony E. English

IPC分类号： C12N13/00 ,  B01D17/06 ,  C12M1/42 ,  C12M1/00 ,  B01D21/28 ,  B06B1/06 ,  B01D17/04 ,  C07K1/14 ,  G10K9/122 ,  H01L41/053 ,  H01L41/09

摘要： A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell culture, which can then be recovered for cell therapy applications. The cell culture continues to expand and reproduce, permitting continuous recovery of cells from the bioreactor.

公开(公告)号：US20170298316A1

公开(公告)日：2017-10-19

申请号：US15634955

申请日：2017-06-27

申请人： FloDesign Sonics, Inc.

发明人： Thomas J. Kennedy, III ,  Bart Lipkens ,  Stanley J. Kowalski, III ,  Anthony E. English

IPC分类号： C12M1/42 ,  C12N13/00 ,  C12M1/00

摘要： A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell culture, which can then be recovered for cell therapy applications. The cell culture continues to expand and reproduce, permitting continuous recovery of cells from the bioreactor.