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公开(公告)号：US10277001B2
公开(公告)日：2019-04-30
申请号：US14938379
申请日：2015-11-11
Applicant: Fotona d.d.
Inventor： Marko Marincek , Janko Nendl , Matjaz Mocnik , Lukac Matjaz
Abstract: A laser system for medical treatment is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one laser pulse of a temporally limited pulse duration (Tp) is generated. The generated laser pulse irradiates some part of the human or animal body so that a two-dimensional laser spot S is located on the top layer of the irradiated part of the human or animal body. The pump power of the pump of the laser system is modulated in such a way that the cumulative energy ES(Tp/2) which is delivered by said laser pulse to said laser spot S during the first half of the pulse duration is less than 45% of the energy ES(Tp) which is delivered by said laser pulse to said laser spot S during the entire pulse duration Tp.
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公开(公告)号：US20160149370A1
公开(公告)日：2016-05-26
申请号：US14938379
申请日：2015-11-11
Applicant: Fotona d.d.
Inventor： Marko Marincek , Janko Nendl , Matjaz Mocnik , Lukac Matjaz
CPC classification number: H01S3/0912 , A61B18/203 , A61B18/245 , A61B2017/00159 , A61B2018/00029 , A61B2018/00476 , A61B2018/00577 , A61B2503/40 , A61N5/06 , A61N2005/067
Abstract: A laser system for medical treatment is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one laser pulse of a temporally limited pulse duration (Tp) is generated. The generated laser pulse irradiates some part of the human or animal body so that a two-dimensional laser spot S is located on the top layer of the irradiated part of the human or animal body. The pump power of the pump of the laser system is modulated in such a way that the cumulative energy ES(Tp/2) which is delivered by said laser pulse to said laser spot S during the first half of the pulse duration is less than 45% of the energy ES(Tp) which is delivered by said laser pulse to said laser spot S during the entire pulse duration Tp.
Abstract translation: 公开了一种用于医疗的激光系统，其包括泵，其中激光系统适于在脉冲操作中操作，使得产生至少一个时间有限的脉冲持续时间（Tp）的激光脉冲。 产生的激光脉冲照射人体或动物体的一部分，使得二维激光斑点S位于人体或动物身体的照射部分的顶层上。 激光系统的泵的泵浦功率被调制成使得在脉冲持续时间的前一半期间由所述激光脉冲传送到所述激光点S的累积能量ES（Tp / 2）小于45 在整个脉冲持续时间Tp期间由所述激光脉冲传送到所述激光点S的能量ES（Tp）的百分比。
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公开(公告)号：US10559938B2
公开(公告)日：2020-02-11
申请号：US14948454
申请日：2015-11-23
Applicant: Fotona d.d.
Inventor： Marko Marincek , Janko Nendl , Matjaz Mocnik , Lukac Matjaz
Abstract: A Laser system is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one individual pulse of a temporally limited pulse duration (T0) is generated, wherein the pulse ablates a material such that a debris cloud forms above the ablated material. Further, the pump power of the pump is modulated in such a way that the following three conditions are fulfilled: (1) the intensity of the pulse oscillates between maximum values and minimum values during the pulse duration, wherein the laser pulse comprises a plurality of intensity maxima Imax which occur at times {Ti, i=1, . . . N}; and a plurality of intensity minima Imin which occur at times {tk, k=1, . . . (N−1)}, wherein the intensity does not vanish at the intensity minima; (2) the intensity oscillations of the laser pulse induce oscillations of the size of the debris cloud so that, during the pulse duration (T0), there are at least two maxima of the size of the debris cloud which occur at times {Tj, j=1, . . . M} and which are located in between two intensity maxima of the laser pulse; and (3) at least 70 percent of the maxima of the size of the debris cloud occur near an intensity minimum of the pulse such that, for at least 70 percent of the maxima of the size of the debris cloud, the intensity of the pulse I(Tj) at the time of the maximum of the size of the debris cloud is smaller than Imin(tk)+0.5×[Imax(Ti)−Imin(tk)], wherein Imin(tk) is the intensity minimum of the pulse which is closest to the maximum of the size of the debris cloud at time Tj and Imax(Ti) is the intensity maximum of the pulse which is closest to the maximum of the size of the debris cloud at time Tj.
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公开(公告)号：US20160149372A1
公开(公告)日：2016-05-26
申请号：US14948454
申请日：2015-11-23
Applicant: Fotona d.d.
Inventor： Marko Marincek , Janko Nendl , Matjaz Mocnik , Lukac Matjaz
Abstract: A Laser system is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one individual pulse of a temporally limited pulse duration (T0) is generated, wherein the pulse ablates a material such that a debris cloud forms above the ablated material. Further, the pump power of the pump is modulated in such a way that the following three conditions are fulfilled: (1) the intensity of the pulse oscillates between maximum values and minimum values during the pulse duration, wherein the laser pulse comprises a plurality of intensity maxima Imax which occur at times {Ti, i=1, . . . N}; and a plurality of intensity minima Imin which occur at times {tk, k=1, . . . (N−1)}, wherein the intensity does not vanish at the intensity minima; (2) the intensity oscillations of the laser pulse induce oscillations of the size of the debris cloud so that, during the pulse duration (T0), there are at least two maxima of the size of the debris cloud which occur at times {tj, J=1, . . . M} and which are located in between two intensity maxima of the laser pulse; and (3) at least 70 percent of the maxima of the size of the debris cloud occur near an intensity minimum of the pulse such that, for at least 70 percent of the maxima of the size of the debris cloud, the intensity of the pulse I(tj) at the time of the maximum of the size of the debris cloud is smaller than Imin(tk)+0.5× [Imax(Ti)−Imin(tk)], wherein Imin(tk) is the intensity minimum of the pulse which is closest to the maximum of the size of the debris cloud at time tj and Imax(Ti) is the intensity maximum of the pulse which is closest to the maximum of the size of the debris cloud at time tj.
Abstract translation: 公开了一种激光系统，其包括泵，其中激光系统适于在脉冲操作中操作，使得产生具有时间上有限的脉冲持续时间（T0）的至少一个单独的脉冲，其中脉冲消融材料，使得 碎片云形成在烧蚀材料之上。 此外，泵的泵功率被调制成满足以下三个条件：（1）脉冲强度在脉冲持续时间期间在最大值和最小值之间振荡，其中激光脉冲包括多个 时间{Ti，i = 1时出现的强度最大值Imax。 。 。 N}; 以及在时间{tk，k = 1，...时出现的多个强度最小值Imin。 。 。 （N-1）}，其中强度不以强度最小值消失; （2）激光脉冲的强度振荡引起碎片云大小的振荡，使得在脉冲持续时间（T0）期间，存在时间{tj， J = 1， 。 。 M}，其位于激光脉冲的两个最大强度之间; 和（3）碎片云大小的最大值的至少70％出现在脉冲的强度最小值附近，使得对于碎片云大小的最大值的至少70％，脉冲的强度 碎片云大小最大时的I（tj）小于Imin（tk）+ 0.5×[Imax（Ti）-Imin（tk）]，其中Imin（tk）是 在时间tj处最接近碎片云大小的最大值的脉冲和Imax（Ti）是在时间tj处最接近碎屑云大小的最大值的脉冲的强度最大值。
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