公开(公告)号：US20240062916A1

公开(公告)日：2024-02-22

申请号：US18039921

申请日：2021-12-02

Applicant: Foundation Medicine, Inc.

Inventor： Leah COMMENT ,  Giovanni PARMIGIANI

IPC: G16H70/20 ,  C12Q1/6855 ,  G16B20/00

CPC classification number: G16H70/20 ,  C12Q1/6855 ,  G16B20/00

Abstract: Methods and systems for determining an expected disease treatment outcome upon treating a subject, methods and devices for selecting a treatment option for the subject, and methods of treating a subject for a disease, are described herein. The method can include receiving a plurality of subject characteristics for the subject; accessing a tree-based model corresponding to a treatment option for the disease, wherein the tree-based model is generated based on a plurality of prior patient characteristics and an associated treatment outcome for the corresponding treatment option; and determining from the plurality of subject characteristics and the tree-based model, an expected treatment outcome for the subject if the subject were treated with the corresponding treatment option.