公开(公告)号：US09110016B2

公开(公告)日：2015-08-18

申请号：US13991295

申请日：2011-12-02

申请人： Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

发明人： Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

IPC分类号： G01N27/447 ,  H01J49/10 ,  B01D59/42 ,  B01D59/44 ,  G01N30/88

CPC分类号： G01N27/44721 ,  B01D59/42 ,  B01D59/44 ,  G01N27/447 ,  G01N27/44717 ,  G01N27/44756 ,  G01N2030/8868 ,  H01J49/105

摘要： A method for isotope measurement of charged species contained in a solution to be analyzed, particularly charged species having an isobaric interference, has the following consecutive steps: a) in the capillary of a capillary electrophoresis device, the solution to be analyzed is inserted contiguously between a terminating electrolyte and a leading electrolyte that, respectively, are placed after the inlet and before the outlet of the capillary and contain ions of the same charge but with mobility inferior and superior to those of said species; b) separating the species by using the capillary electrophoresis device according to the isotachophoresis mode; then c) in the continuity of the preceding step, performing an isotope measurement of the species detected in the form of a substantially constant amplitude signal by using an inductively coupled plasma mass spectrometer (ICPMS) connected by direct coupling with the capillary electrophoresis device.

摘要翻译： 在待分析溶液中所含的带电物质的同位素测量方法，特别是具有等压干扰的带电物质的方法具有以下连续步骤：a）在毛细管电泳装置的毛细管中，待分析溶液相邻插入 末端电解质和前导电解质，其分别放置在毛细管的入口之后并且在毛细管的出口之前并且含有相同电荷的离子，但其迁移率低于和优于所述物质的离子; b）根据等电泳方式使用毛细管电泳装置分离物种; 然后c）在前述步骤的连续性中，通过使用通过与毛细管电泳装置直接耦合连接的电感耦合等离子体质谱仪（ICPMS），以基本上恒定幅度信号的形式检测的物种进行同位素测量。

公开(公告)号：US20130248365A1

公开(公告)日：2013-09-26

申请号：US13991295

申请日：2011-12-02

申请人： Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

发明人： Frédéric Chartier ,  Valérie Geersten ,  Laurent Vio ,  Gérard Crétier

IPC分类号： G01N27/447

CPC分类号： G01N27/44721 ,  B01D59/42 ,  B01D59/44 ,  G01N27/447 ,  G01N27/44717 ,  G01N27/44756 ,  G01N2030/8868 ,  H01J49/105

摘要： A method for isotope measurement of charged species contained in a solution to be analyzed, particularly charged species having an isobaric interference, has the following consecutive steps: a) in the capillary of a capillary electrophoresis device, the solution to be analyzed is inserted contiguously between a terminating electrolyte and a leading electrolyte that, respectively, are placed after the inlet and before the outlet of the capillary and contain ions of the same charge but with mobility inferior and superior to those of said species; b) separating the species by using the capillary electrophoresis device according to the isotachophoresis mode; then c) in the continuity of the preceding step, performing an isotope measurement of the species detected in the form of a substantially constant amplitude signal by using an inductively coupled plasma mass spectrometer (ICPMS) connected by direct coupling with the capillary electrophoresis device.

摘要翻译： 在待分析溶液中所含的带电物质的同位素测量方法，特别是具有等压干扰的带电物质的方法具有以下连续步骤：a）在毛细管电泳装置的毛细管中，待分析溶液相邻插入 末端电解质和前导电解质，其分别放置在毛细管的入口之后并且在毛细管的出口之前并且含有相同电荷的离子，但其迁移率低于和优于所述物质的离子; b）根据等电泳方式使用毛细管电泳装置分离物种; 然后c）在前述步骤的连续性中，通过使用通过与毛细管电泳装置直接耦合连接的电感耦合等离子体质谱仪（ICPMS），以基本上恒定幅度信号的形式检测的物种进行同位素测量。