公开(公告)号：US06613898B1

公开(公告)日：2003-09-02

申请号：US09366065

申请日：1999-08-02

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： C07G1700

CPC分类号： C08B30/18

摘要： Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by catalytically hydrogenating the mixture under reaction conditions sufficient to preserve the DP profile of the mixture, which reaction conditions typically include a reaction temperature ranging from about 50° C. to about 150° C. and a reaction pressure ranging up to about 1500 psi. Surprisingly, when the mixture is a malto-oligosaccharide mixture, the reduced mixture will have a superior color-fastness and thermal stability as compared to a similar unreduced mixture of malto-oligosaccharides, and also low reactivity towards nitrogen-containing species.

公开(公告)号：US06593469B1

公开(公告)日：2003-07-15

申请号：US09693496

申请日：2000-10-20

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： C07H100

CPC分类号： A01N1/0226 ,  A01N1/02 ,  A23G3/0205 ,  A23G2200/06 ,  A23L3/3562 ,  C09K15/06

摘要： Disclosed is a composition that includes a material that is susceptible to degradation and a preserving agent in an amount effective to preserve the material comprising one or more reduced malto-oligosaccharide species. The preserving agent can include a single reduced malto-oligosaccharide species or a plurality of such species. Further disclosed is a method of preserving a material. The method generally includes contacting the material with a preserving agent containing a preserving effective amount of one or more reduced malto-oligosaccharide species. Solutions, powders, glasses, gels, and the like containing the chemically reactive material(s) and a preserving effective amount of one or more reduced malto-oligosaccharide species may be prepared.

摘要翻译： 公开了一种组合物，其包含易于降解的材料和防腐剂，其量有效地保护包含一种或多种还原的麦芽低聚物种的材料。 防腐剂可以包括单一还原的麦芽寡糖物种或多种这样的物质。 进一步公开的是保存材料的方法。 该方法通常包括使材料与含有保存有效量的一种或多种还原的麦芽低聚物种类的防腐剂接触。 可以制备含有化学反应性物质的溶液，粉末，玻璃，凝胶等，并且可以制备保存有效量的一种或多种还原的麦芽低聚糖物质。

公开(公告)号：US06391293B1

公开(公告)日：2002-05-21

申请号：US09693497

申请日：2000-10-20

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： A61K709

CPC分类号： A61K8/60 ,  A61K8/19 ,  A61K8/43 ,  A61Q5/04

摘要： Disclosed is a lanthionizing composition that comprises a lanthionizing agent, such as guanidine hydroxide or sodium hydroxide, and a reduced malto-oligosaccharide. Also disclosed is a method for lanthionization, the method comprising applying to the hair the lanthionizing composition of the invention.

摘要翻译： 公开了一种除磷酸盐组合物，其包含一种除磷剂，例如氢氧化胍或氢氧化钠，以及还原的麦芽低聚糖。 还公开了一种用于去磷酸化的方法，该方法包括向头发施用本发明的去脂组合物。

公开(公告)号：US07405293B1

公开(公告)日：2008-07-29

申请号：US10653037

申请日：2003-08-29

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： C08B30/12

CPC分类号： C08B30/18

摘要： Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by catalytically hydrogenating the mixture under reaction conditions sufficient to preserve the DP profile of the mixture, which reaction conditions typically include a reaction temperature ranging from about 50° C. to about 150° C. and a reaction pressure ranging up to about 1500 psi. Surprisingly, when the mixture is a malto-oligosaccharide mixture, the reduced mixture will have a superior color-fastness and thermal stability as compared to a similar unreduced mixture of malto-oligosaccharides, and also low reactivity towards nitrogen-containing species.

摘要翻译： 公开了由此制备的寡糖混合物和寡糖混合物的还原方法。 根据所公开的发明，具有给定DP分布的寡糖的混合物通过在足以保持混合物的DP分布的反应条件下催化氢化混合物而还原为DE，该反应条件通常包括反应温度 范围为约50℃至约150℃，反应压力范围高达约1500psi。 令人吃惊的是，当混合物是麦芽低聚糖混合物时，与类似的未还原的麦芽寡糖混合物相比，还原的混合物具有优异的耐色牢度和热稳定性，并且对含氮物质的反应性低。

公开(公告)号：US06919446B1

公开(公告)日：2005-07-19

申请号：US09614961

申请日：2000-07-13

申请人： Richard L. Antrim ,  Frank W. Barresi

发明人： Richard L. Antrim ,  Frank W. Barresi

IPC分类号： C07H3/06 ,  C07B61/00 ,  C07H1/00 ,  C07H15/04 ,  C08B30/18 ,  C08B31/00 ,  C08B37/00 ,  C07G17/00 ,  C13K7/00

CPC分类号： C08B30/18 ,  C08B31/00

摘要： Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by catalytically hydrogenating the mixture under reaction conditions sufficient to preserve the DP profile of the mixture, which reaction conditions typically include a reaction temperature ranging from about 50° C. to about 150° C. and a reaction pressure of at least about 1500 psi. Surprisingly, when the mixture is a malto-oligosaccharide mixture, the reduced mixture will have a superior color-fastness and thermal stability as compared to a similar unreduced mixture of malto-oligosaccharides, and also low reactivity towards nitrogen-containing species.

摘要翻译： 公开了由此制备的寡糖混合物和寡糖混合物的还原方法。 根据所公开的发明，具有给定DP分布的寡糖的混合物通过在足以保持混合物的DP分布的反应条件下催化氢化混合物而还原为DE，该反应条件通常包括反应温度 范围为约50℃至约150℃，反应压力为至少约1500psi。 令人吃惊的是，当混合物是麦芽低聚糖混合物时，与类似的未还原的麦芽寡糖混合物相比，还原的混合物具有优异的耐色牢度和热稳定性，并且对含氮物质的反应性低。

公开(公告)号：US06828310B2

公开(公告)日：2004-12-07

申请号：US10360538

申请日：2003-02-06

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： A61K31715

CPC分类号： A01N1/0226 ,  A01N1/02 ,  A23G3/0205 ,  A23G2200/06 ,  A23L3/3562 ,  C09K15/06

摘要： Disclosed is a composition that includes a material that is susceptible to degradation and a preserving agent in an amount effective to preserve the material comprising one or more reduced malto-oligosaccharide species. The preserving agent can include a single reduced malto-oligosaccharide species or a plurality of such species. Further disclosed is a method of preserving a material. The method generally includes contacting the material with a preserving agent containing a preserving effective amount of one or more reduced malto-oligosaccharide species. Solutions, powders, glasses, gels, and the like containing the chemically reactive material(s) and a preserving effective amount of one or more reduced malto-oligosaccharide species may be prepared.

摘要翻译： 公开了一种组合物，其包含易于降解的材料和防腐剂，其量有效地保护包含一种或多种还原的麦芽低聚物种的材料。 防腐剂可以包括单一还原的麦芽寡糖物种或多种这样的物质。 进一步公开的是保存材料的方法。 该方法通常包括使材料与含有保存有效量的一种或多种还原的麦芽低聚物种类的防腐剂接触。 可以制备含有化学反应性物质的溶液，粉末，玻璃，凝胶等，并且可以制备保存有效量的一种或多种还原的麦芽低聚糖物质。

公开(公告)号：US07728125B2

公开(公告)日：2010-06-01

申请号：US12145262

申请日：2008-06-24

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： A61K31/718

CPC分类号： C08B30/18

摘要： Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by catalytically hydrogenating the mixture under reaction conditions sufficient to preserve the DP profile of the mixture, which reaction conditions typically include a reaction temperature ranging from about 50° C. to about 150° C. and a reaction pressure ranging up to about 1500 psi. Surprisingly, when the mixture is a malto-oligosaccharide mixture, the reduced mixture will have a superior color-fastness and thermal stability as compared to a similar unreduced mixture of malto-oligosaccharides, and also low reactivity towards nitrogen-containing species.

摘要翻译： 公开了由此制备的寡糖混合物和寡糖混合物的还原方法。 根据所公开的发明，具有给定DP分布的寡糖的混合物通过在足以保持混合物的DP分布的反应条件下催化氢化混合物而还原为DE，该反应条件通常包括反应温度 范围为约50℃至约150℃，反应压力范围高达约1500psi。 令人吃惊的是，当混合物是麦芽低聚糖混合物时，与类似的未还原的麦芽寡糖混合物相比，还原的混合物具有优异的耐色牢度和热稳定性，并且对含氮物质的反应性低。

公开(公告)号：US06720418B2

公开(公告)日：2004-04-13

申请号：US10023077

申请日：2001-12-13

申请人： Richard L. Antrim ,  Frank W. Barresi

发明人： Richard L. Antrim ,  Frank W. Barresi

IPC分类号： C08B3100

CPC分类号： C12P7/62 ,  A23L29/35 ,  C08B31/00

摘要： Disclosed are derivatized malto-oligosaccharides and methods for the preparation thereof. In accordance with the disclosed invention, a malto-oligosaccharide is hydrogenated to thereby obtain a hydrogenated malto-oligosaccharide, and the resulting hydrogenated malto-oligosaccharide is derivatized, such as via oxidation, esterification, etherification, or enzymatic modification. The derivatization of such hydrogenated malto-oligosaccharides results in a surprisingly low level of a formation of by-products and products of degradation. In a particularly preferred embodiment of the invention, a mixture of malto-oligosaccharides is catalytically hydrogenated under reaction conditions suitable to substantially preserve the degree of polymerization (DP) profile of the mixture. The resulting malto-oligosaccharide mixture then is derivatized to form a derivatized malto-oligosaccharide mixture.

摘要翻译： 公开了衍生化的麦芽低聚糖及其制备方法。 根据所公开的发明，将麦芽低聚糖氢化，由此得到氢化的低聚麦芽糖，所得氢化的麦芽寡糖通过氧化，酯化，醚化或酶改性而被衍生化。 这种氢化麦芽寡糖的衍生化导致副产物和降解产物形成的惊人的低水平。 在本发明的一个特别优选的实施方案中，麦芽寡糖的混合物在适于基本上保持混合物的聚合度（DP）轮廓的反应条件下被催化氢化。 然后将所得的麦芽低聚糖混合物衍生化以形成衍生化的麦芽低聚糖混合物。

公开(公告)号：US06380379B1

公开(公告)日：2002-04-30

申请号：US09378673

申请日：1999-08-20

申请人： Richard L. Antrim ,  Frank W. Barresi

发明人： Richard L. Antrim ,  Frank W. Barresi

IPC分类号： C08B3100

CPC分类号： C12P7/62 ,  A23L29/35 ,  C08B31/00

摘要： Disclosed are derivatized malto-oligosaccharides and methods for the preparation thereof. In accordance with the disclosed invention, a malto-oligosaccharide is hydrogenated to thereby obtain a hydrogenated malto-oligosaccharide, and the resulting hydrogenated malto-oligosaccharide is derivatized, such as via oxidation, esterification, etherification, or enzymatic modification. The derivatization of such hydrogenated malto-oligosaccharides results in a surprisingly low level of a formation of by-products and products of degradation. In a particularly preferred embodiment of the invention, a mixture of malto-oligosaccharides is catalytically hydrogenated under reaction conditions suitable to substantially preserve the degree of polymerization (DP) profile of the mixture. The resulting malto-oligosaccharide mixture then is derivatized to form a derivatized malto-oligosaccharide mixture.

公开(公告)号：US07595393B2

公开(公告)日：2009-09-29

申请号：US10963681

申请日：2004-10-13

申请人： Frank W. Barresi ,  Richard L. Antrim

发明人： Frank W. Barresi ,  Richard L. Antrim

IPC分类号： C08B31/00 ,  C07H3/06 ,  C07H1/00

CPC分类号： C08B30/18

摘要： Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by catalytically hydrogenating the mixture under reaction conditions sufficient to preserve the DP profile of the mixture, which reaction conditions typically include a reaction temperature ranging from about 50° C. to about 150° C. and a reaction pressure ranging up to about 1500 psi. Surprisingly, when the mixture is a malto-oligosaccharide mixture, the reduced mixture will have a superior color-fastness and thermal stability as compared to a similar unreduced mixture of malto-oligosaccharides, and also low reactivity towards nitrogen-containing species.

摘要翻译： 公开了由此制备的寡糖混合物和寡糖混合物的还原方法。 根据所公开的发明，具有给定DP分布的寡糖的混合物通过在足以保持混合物的DP分布的反应条件下催化氢化混合物而还原为DE，该反应条件通常包括反应温度 范围为约50℃至约150℃，反应压力范围高达约1500psi。 令人吃惊的是，当混合物是麦芽低聚糖混合物时，与类似的未还原的麦芽寡糖混合物相比，还原的混合物具有优异的耐色牢度和热稳定性，并且对含氮物质的反应性低。