Substituted arylamide oxazepinopyrimidone derivatives
    9.
    发明授权
    Substituted arylamide oxazepinopyrimidone derivatives 有权
    取代的芳酰胺氧氮杂嘧啶衍生物

    公开(公告)号:US08507470B2

    公开(公告)日:2013-08-13

    申请号:US12844275

    申请日:2010-07-27

    IPC分类号: C07D498/04

    CPC分类号: C07D498/04

    摘要: The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: wherein: Y, Z, R1, R2, R3, R4 and n are as defined in the disclosure. Also disclosed are methods of preparing the compounds of formula (I), intermediates therefor and their utility in treating a variety of disease conditions.

    摘要翻译: 本发明涉及由式(I)表示的一系列嘧啶酮衍生物或其盐,或其溶剂合物或其水合物:其中:Y,Z,R 1,R 2,R 3,R 4和n如本公开所定义。 还公开了制备式(I)化合物,其中间体及其在治疗各种疾病状况中的用途的方法。