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公开(公告)号：US20170252449A1
公开(公告)日：2017-09-07
申请号：US15448363
申请日：2017-03-02
IPC分类号： A61K47/34 , A61K31/19 , A61K45/06 , A61K31/5517 , A61K9/00
CPC分类号： A61K47/34 , A61K9/0046 , A61K31/19 , A61K31/5517 , A61K45/06
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20170252329A1
公开(公告)日：2017-09-07
申请号：US15448362
申请日：2017-03-02
IPC分类号： A61K31/4439 , A61K31/19 , A61K45/06 , A61K47/34 , A61K9/00
CPC分类号： A61K31/4439 , A61K9/0046 , A61K9/08 , A61K31/20 , A61K45/06 , A61K47/10 , A61K47/34 , A61K2300/00
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20190336490A1
公开(公告)日：2019-11-07
申请号：US16376764
申请日：2019-04-05
IPC分类号： A61K31/46 , A61K31/40 , A61K31/24 , A61K31/222 , A61K31/4465 , A61K31/501 , A61K31/5377 , A61K31/55 , A61K31/517 , A61K31/4453 , A61K9/00 , A61P21/00
摘要： Provided are compositions and methods comprising a MAChR antagonist/inverse agonist/partial agonist and a histamine H3 receptor antagonist/inverse agonist/partial agonist for increasing proliferation Oligodendrocyte Progenitor Cells (OPCs) into mature, myelinating oligodendrocytes, and related methods of treating demyelination disorders.
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公开(公告)号：US20190201398A1
公开(公告)日：2019-07-04
申请号：US16227117
申请日：2018-12-20
IPC分类号： A61K31/506 , A61L27/38 , A61L27/18 , A61K9/06 , A61K9/10 , A61K9/00 , A61K47/10 , A61K45/06 , A61K31/19
CPC分类号： A61K31/506 , A61K9/0046 , A61K9/06 , A61K9/10 , A61K31/19 , A61K31/4439 , A61K45/06 , A61K47/10 , A61L27/18 , A61L27/3834 , A61L27/3839 , C08L71/02 , A61K2300/00
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20220096639A1
公开(公告)日：2022-03-31
申请号：US17492131
申请日：2021-10-01
IPC分类号： A61K47/34 , A61K47/12 , A61K31/506 , A61K31/4439 , A61K31/551 , A61K9/00
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20170252450A1
公开(公告)日：2017-09-07
申请号：US15448420
申请日：2017-03-02
IPC分类号： A61K47/34 , A61K31/19 , A61K45/06 , A61K31/5377 , A61K9/00
CPC分类号： A61K47/34 , A61K9/0046 , A61K31/19 , A61K31/5377 , A61K45/06 , A61K2300/00
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20170252448A1
公开(公告)日：2017-09-07
申请号：US15447682
申请日：2017-03-02
IPC分类号： A61K47/34 , A61K31/551 , A61K31/4439 , A61K47/12 , A61K31/506
CPC分类号： A61K47/34 , A61K9/0019 , A61K31/4439 , A61K31/506 , A61K31/551 , A61K47/12
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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8.发明申请公开(公告)号：US20170252340A1
公开(公告)日：2017-09-07
申请号：US15448419
申请日：2017-03-02
CPC分类号： A61K31/506 , A61K9/0046 , A61K9/06 , A61K9/10 , A61K31/19 , A61K31/4439 , A61K45/06 , A61K47/10 , A61L27/18 , A61L27/3834 , A61L27/3839 , C08L71/02
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20210260061A1
公开(公告)日：2021-08-26
申请号：US17317972
申请日：2021-05-12
IPC分类号： A61K31/506 , A61K31/19 , A61K45/06 , A61K47/10 , A61K9/00 , A61K9/10 , A61K9/06 , A61L27/18 , A61L27/38
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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公开(公告)号：US20190231880A1
公开(公告)日：2019-08-01
申请号：US16239786
申请日：2019-01-04
IPC分类号： A61K47/34 , A61K9/00 , A61K47/12 , A61K31/506 , A61K31/4439 , A61K31/551
CPC分类号： A61K47/34 , A61K9/0019 , A61K31/4439 , A61K31/506 , A61K31/551 , A61K47/12
摘要： The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
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