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公开(公告)号：US20120179221A1
公开(公告)日：2012-07-12
申请号：US13422622
申请日：2012-03-16
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565 , A61N1/362
摘要： A system for therapeutically stimulating a His bundle includes an implantable pulse generator and a multi-polar medical electrical lead. The generator is configured for subcutaneous implantation and to generate a pacing stimulus. The lead includes a connector assembly, a flexible tubular body, a distal tip assembly and coil conductors. The body extends intravascularly from the generator to a location proximate the His bundle and includes a proximal end, a distal end, and a longitudinal lumen. The tip assembly includes an electrode, a fixation helix, and a shank portion. The helix extends to a location proximate the His bundle and is operable as an electrically isolated electrode. The shank portion extends within the lumen and includes a receptacle for receiving a stylet tip. The conductors extend longitudinally through the lumen and are coupled to the electrode and the helix. One or both of the conductors defines a stylet lumen.
摘要翻译： 用于治疗性刺激His束的系统包括可植入脉冲发生器和多极医疗电引线。 发生器被配置用于皮下植入并产生起搏刺激。 引线包括连接器组件，柔性管状体，远端尖端组件和线圈导体。 身体从发生器血管内延伸到靠近His束的位置，并且包括近端，远端和纵向内腔。 尖端组件包括电极，固定螺旋和柄部分。 螺旋线延伸到靠近His束的位置，并且可操作为电隔离电极。 柄部分在内腔内延伸并且包括用于接收通球针尖端的容器。 导体纵向延伸穿过内腔，并与电极和螺旋结合。 一个或两个导体限定了探针管腔。
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公开(公告)号：US20110197440A1
公开(公告)日：2011-08-18
申请号：US13094514
申请日：2011-04-26
IPC分类号： H01R43/20
CPC分类号： A61N1/056 , A61N1/0573 , Y10T29/49117 , Y10T29/49208
摘要： A medical electrical lead configured to be coupled to a pulse generator in a cardiac rhythm management system. The lead comprises a proximal terminal connector configured for coupling the lead to the pulse generator, and a plurality of longitudinally arranged lead segments each configured to exhibit one or more predetermined physical characteristics based on the implantation location for the respective segment. The lead segments may be pre-fabricated as separate modules optimized for the operating environment and/or delivery requirements of the respective segments. The pre-fabricated modules are longitudinally arranged and joined to form the lead.
摘要翻译： 一种医疗电引线，被配置为耦合到心律管理系统中的脉冲发生器。 引线包括被配置为将引线耦合到脉冲发生器的近端端子连接器，以及多个纵向排列的引线段，每个引导段被配置为基于相应段的注入位置呈现一个或多个预定的物理特性。 引线段可以被预制成针对各个段的操作环境和/或传送要求而优化的单独模块。 预制模块纵向排列并连接以形成引线。
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公开(公告)号：US20090259272A1
公开(公告)日：2009-10-15
申请号：US12424298
申请日：2009-04-15
IPC分类号： A61N1/362
CPC分类号： A61N1/0573 , A61N1/0565 , A61N1/362
摘要： A system for therapeutically stimulating a His bundle includes an implantable pulse generator and a multi-polar medical electrical lead. The generator is configured for subcutaneous implantation and to generate a pacing stimulus. The lead includes a connector assembly, a flexible tubular body, a distal tip assembly and coil conductors. The body extends intravascularly from the generator to a location proximate the His bundle and includes a proximal end, a distal end, and a longitudinal lumen. The tip assembly includes an electrode, a fixation helix, and a shank portion. The helix extends to a location proximate the His bundle and is operable as an electrically isolated electrode. The shank portion extends within the lumen and includes a receptacle for receiving a stylet tip. The conductors extend longitudinally through the lumen and are coupled to the electrode and the helix. One or both of the conductors defines a stylet lumen.
摘要翻译： 用于治疗性刺激His束的系统包括可植入脉冲发生器和多极医疗电引线。 发生器被配置用于皮下植入并产生起搏刺激。 引线包括连接器组件，柔性管状体，远端尖端组件和线圈导体。 身体从发生器血管内延伸到靠近His束的位置，并且包括近端，远端和纵向内腔。 尖端组件包括电极，固定螺旋和柄部分。 螺旋线延伸到靠近His束的位置，并且可操作为电隔离电极。 柄部分在内腔内延伸并且包括用于接收通球针尖端的容器。 导体纵向延伸穿过内腔，并与电极和螺旋结合。 一个或两个导体限定了探针管腔。
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公开(公告)号：US20090210044A1
公开(公告)日：2009-08-20
申请号：US12371268
申请日：2009-02-13
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , Y10T29/49117 , Y10T29/49208
摘要： A medical electrical lead configured to be coupled to a pulse generator in a cardiac rhythm management system. The lead comprises a proximal terminal connector configured for coupling the lead to the pulse generator, and a plurality of longitudinally arranged lead segments each configured to exhibit one or more predetermined physical characteristics based on the implantation location for the respective segment. The lead segments may be pre-fabricated as separate modules optimized for the operating environment and/or delivery requirements of the respective segments. The pre-fabricated modules are longitudinally arranged and joined to form the lead.
摘要翻译： 一种医疗电引线，被配置为耦合到心律管理系统中的脉冲发生器。 引线包括被配置为将引线耦合到脉冲发生器的近端端子连接器，以及多个纵向排列的引线段，每个引导段被配置为基于相应段的注入位置呈现一个或多个预定的物理特性。 引线段可以被预制成针对各个段的操作环境和/或传送要求而优化的单独模块。 预制模块纵向排列并连接以形成引线。
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公开(公告)号：US08099176B2
公开(公告)日：2012-01-17
申请号：US13094514
申请日：2011-04-26
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/0573 , Y10T29/49117 , Y10T29/49208
摘要： A medical electrical lead configured to be coupled to a pulse generator in a cardiac rhythm management system. The lead comprises a proximal terminal connector configured for coupling the lead to the pulse generator, and a plurality of longitudinally arranged lead segments each configured to exhibit one or more predetermined physical characteristics based on the implantation location for the respective segment. The lead segments may be pre-fabricated as separate modules optimized for the operating environment and/or delivery requirements of the respective segments. The pre-fabricated modules are longitudinally arranged and joined to form the lead.
摘要翻译： 一种医疗电引线，被配置为耦合到心律管理系统中的脉冲发生器。 引线包括被配置为将引线耦合到脉冲发生器的近端端子连接器，以及多个纵向排列的引线段，每个引导段被配置为基于相应段的注入位置呈现一个或多个预定的物理特性。 引线段可以被预制成针对各个段的操作环境和/或传送要求而优化的单独模块。 预制模块纵向排列并连接以形成引线。
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公开(公告)号：US07946980B2
公开(公告)日：2011-05-24
申请号：US12371268
申请日：2009-02-13
IPC分类号： A61B1/04
CPC分类号： A61N1/056 , A61N1/0573 , Y10T29/49117 , Y10T29/49208
摘要： A medical electrical lead configured to be coupled to a pulse generator in a cardiac rhythm management system. The lead comprises a proximal terminal connector configured for coupling the lead to the pulse generator, and a plurality of longitudinally arranged lead segments each configured to exhibit one or more predetermined physical characteristics based on the implantation location for the respective segment. The lead segments may be pre-fabricated as separate modules optimized for the operating environment and/or delivery requirements of the respective segments. The pre-fabricated modules are longitudinally arranged and joined to form the lead.
摘要翻译： 一种医疗电引线，被配置为耦合到心律管理系统中的脉冲发生器。 引线包括被配置为将引线耦合到脉冲发生器的近端端子连接器，以及多个纵向排列的引线段，每个引导段被配置为基于相应段的注入位置呈现一个或多个预定的物理特性。 引线段可以被预制成针对各个段的操作环境和/或传送要求而优化的单独模块。 预制模块纵向排列并连接以形成引线。
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公开(公告)号：US08406899B2
公开(公告)日：2013-03-26
申请号：US13422622
申请日：2012-03-16
IPC分类号： A61N1/00
CPC分类号： A61N1/0573 , A61N1/0565 , A61N1/362
摘要： A system for therapeutically stimulating a His bundle includes an implantable pulse generator and a multi-polar medical electrical lead. The generator is configured for subcutaneous implantation and to generate a pacing stimulus. The lead includes a connector assembly, a flexible tubular body, a distal tip assembly and coil conductors. The body extends intravascularly from the generator to a location proximate the His bundle and includes a proximal end, a distal end, and a longitudinal lumen. The tip assembly includes an electrode, a fixation helix, and a shank portion. The helix extends to a location proximate the His bundle and is operable as an electrically isolated electrode. The shank portion extends within the lumen and includes a receptacle for receiving a stylet tip. The conductors extend longitudinally through the lumen and are coupled to the electrode and the helix. One or both of the conductors defines a stylet lumen.
摘要翻译： 用于治疗性刺激His束的系统包括可植入脉冲发生器和多极医疗电引线。 发生器被配置用于皮下植入并产生起搏刺激。 引线包括连接器组件，柔性管状体，远端尖端组件和线圈导体。 身体从发生器血管内延伸到靠近His束的位置，并且包括近端，远端和纵向内腔。 尖端组件包括电极，固定螺旋和柄部分。 螺旋线延伸到靠近His束的位置，并且可操作为电隔离电极。 柄部分在内腔内延伸并且包括用于接收通球针尖端的容器。 导体纵向延伸穿过内腔，并与电极和螺旋结合。 一个或两个导体限定了探针管腔。
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公开(公告)号：US08712553B2
公开(公告)日：2014-04-29
申请号：US12962475
申请日：2010-12-07
申请人： G. Shantanu Reddy
发明人： G. Shantanu Reddy
CPC分类号： A61N1/057 , A61N1/0573 , A61N2001/0578
摘要： According to embodiments of the present invention, a cardiac lead system adapted for fixation to a vessel including an expandable fixation mechanism adapted to engage an inner surface of the vessel and a lead member comprising an anchor structure at distal end, the anchor structure configured to removably engage with fixation mechanism. Such anchor structure may be helical, and may removably engage fixation mechanism upon rotation or an application of torque, and may be extendable and/or retractable. Fixation mechanism may be polymer coated weave and/or mesh to trap anchor structure. Lead member and/or fixation mechanism may include electrodes and/or sensors, and lead member may include L-shape, S-shape, spiral, and/or sinusoidal shape for positioning of electrodes and/or sensors or for facilitated engagement of anchor structure. A guide wire attached to fixation mechanism during deployment may, prior to detachment, serve to guide lead member to a target site at fixation mechanism.
摘要翻译： 根据本发明的实施例，适于固定在容器上的心脏引导系统包括适于接合血管内表面的可扩张固定机构和在远端包括锚结构的引导部件，所述锚固结构构造成可移除地 参与固定机制。 这种锚结构可以是螺旋形的，并且可以在旋转或施加扭矩时可移除地接合固定机构，并且可以是可延伸的和/或可缩回的。 固定机构可以是聚合物涂层编织和/或网格以捕获锚结构。 引线构件和/或固定机构可以包括电极和/或传感器，并且引线构件可以包括用于定位电极和/或传感器的L形，S形，螺旋形和/或正弦形状，或者用于锚结构的便于接合 。 在展开期间附接到固定机构的引导线可以在分离之前用于在固定机构处将引导部件引导到目标部位。
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公开(公告)号：US08532792B2
公开(公告)日：2013-09-10
申请号：US13110351
申请日：2011-05-18
申请人： G. Shantanu Reddy , Ryan Kleve , Adam J. Rivard
发明人： G. Shantanu Reddy , Ryan Kleve , Adam J. Rivard
CPC分类号： A61N1/0573 , A61N2001/0578
摘要： An active fixation implantable medical lead may include an electrode base that is configured to accommodate an extraction stylet that may be used if the fixation helix is not otherwise easily retracted. An extraction tool may be used in combination with the extraction stylet in extraction techniques designed for retraction of a fixation helix.
摘要翻译： 主动固定可植入医疗引线可以包括电极基座，其被配置为容纳可以使用的提取探针，如果固定螺旋不能容易地缩回。 提取工具可以与设计用于收缩固定螺旋的提取技术中的提取探针组合使用。
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公开(公告)号：US08249720B2
公开(公告)日：2012-08-21
申请号：US12265282
申请日：2008-11-05
申请人： Kevin E. Verzal , Adam J. Rivard , Mohan Krishnan , G. Shantanu Reddy , Patsy A. Coppola , Edward L. Dickinson , Andrew C. Harvey
发明人： Kevin E. Verzal , Adam J. Rivard , Mohan Krishnan , G. Shantanu Reddy , Patsy A. Coppola , Edward L. Dickinson , Andrew C. Harvey
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0582
摘要： An implantable medical system includes a medical lead including an insulating sheath and a conductor and an anchoring device. The anchoring device defines an inner lumen adapted to coaxially receive the medical lead, where the inner lumen has an effective diameter. The anchoring device includes a sleeve including a substantially elongate body defining an outer surface and an inner bore. The anchoring device also has a compression member including a first end, a second end, and an intermediate portion between the first and second ends. The compression member is at least partially embedded in the sleeve such that compression of the first and second ends of the compression member toward one another causes the effective diameter of at least a portion of the inner lumen of the anchoring device to reversibly increase.
摘要翻译： 可植入医疗系统包括包括绝缘护套和导体的医疗引线和锚定装置。 锚定装置限定适于同轴地接纳医疗引线的内腔，其中内腔具有有效直径。 锚固装置包括套筒，其包括限定外表面和内孔的基本上细长的主体。 锚定装置还具有包括第一端部，第二端部和第一端部和第二端部之间的中间部分的压缩构件。 压缩构件至少部分地嵌入在套筒中，使得压缩构件的第一和第二端部彼此朝向彼此的压缩导致锚定装置的内腔的至少一部分的有效直径可逆地增加。
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