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公开(公告)号：US08712553B2
公开(公告)日：2014-04-29
申请号：US12962475
申请日：2010-12-07
申请人： G. Shantanu Reddy
发明人： G. Shantanu Reddy
CPC分类号： A61N1/057 , A61N1/0573 , A61N2001/0578
摘要： According to embodiments of the present invention, a cardiac lead system adapted for fixation to a vessel including an expandable fixation mechanism adapted to engage an inner surface of the vessel and a lead member comprising an anchor structure at distal end, the anchor structure configured to removably engage with fixation mechanism. Such anchor structure may be helical, and may removably engage fixation mechanism upon rotation or an application of torque, and may be extendable and/or retractable. Fixation mechanism may be polymer coated weave and/or mesh to trap anchor structure. Lead member and/or fixation mechanism may include electrodes and/or sensors, and lead member may include L-shape, S-shape, spiral, and/or sinusoidal shape for positioning of electrodes and/or sensors or for facilitated engagement of anchor structure. A guide wire attached to fixation mechanism during deployment may, prior to detachment, serve to guide lead member to a target site at fixation mechanism.
摘要翻译： 根据本发明的实施例，适于固定在容器上的心脏引导系统包括适于接合血管内表面的可扩张固定机构和在远端包括锚结构的引导部件，所述锚固结构构造成可移除地 参与固定机制。 这种锚结构可以是螺旋形的，并且可以在旋转或施加扭矩时可移除地接合固定机构，并且可以是可延伸的和/或可缩回的。 固定机构可以是聚合物涂层编织和/或网格以捕获锚结构。 引线构件和/或固定机构可以包括电极和/或传感器，并且引线构件可以包括用于定位电极和/或传感器的L形，S形，螺旋形和/或正弦形状，或者用于锚结构的便于接合 。 在展开期间附接到固定机构的引导线可以在分离之前用于在固定机构处将引导部件引导到目标部位。
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公开(公告)号：US08532792B2
公开(公告)日：2013-09-10
申请号：US13110351
申请日：2011-05-18
申请人： G. Shantanu Reddy , Ryan Kleve , Adam J. Rivard
发明人： G. Shantanu Reddy , Ryan Kleve , Adam J. Rivard
CPC分类号： A61N1/0573 , A61N2001/0578
摘要： An active fixation implantable medical lead may include an electrode base that is configured to accommodate an extraction stylet that may be used if the fixation helix is not otherwise easily retracted. An extraction tool may be used in combination with the extraction stylet in extraction techniques designed for retraction of a fixation helix.
摘要翻译： 主动固定可植入医疗引线可以包括电极基座，其被配置为容纳可以使用的提取探针，如果固定螺旋不能容易地缩回。 提取工具可以与设计用于收缩固定螺旋的提取技术中的提取探针组合使用。
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公开(公告)号：US08249720B2
公开(公告)日：2012-08-21
申请号：US12265282
申请日：2008-11-05
申请人： Kevin E. Verzal , Adam J. Rivard , Mohan Krishnan , G. Shantanu Reddy , Patsy A. Coppola , Edward L. Dickinson , Andrew C. Harvey
发明人： Kevin E. Verzal , Adam J. Rivard , Mohan Krishnan , G. Shantanu Reddy , Patsy A. Coppola , Edward L. Dickinson , Andrew C. Harvey
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0582
摘要： An implantable medical system includes a medical lead including an insulating sheath and a conductor and an anchoring device. The anchoring device defines an inner lumen adapted to coaxially receive the medical lead, where the inner lumen has an effective diameter. The anchoring device includes a sleeve including a substantially elongate body defining an outer surface and an inner bore. The anchoring device also has a compression member including a first end, a second end, and an intermediate portion between the first and second ends. The compression member is at least partially embedded in the sleeve such that compression of the first and second ends of the compression member toward one another causes the effective diameter of at least a portion of the inner lumen of the anchoring device to reversibly increase.
摘要翻译： 可植入医疗系统包括包括绝缘护套和导体的医疗引线和锚定装置。 锚定装置限定适于同轴地接纳医疗引线的内腔，其中内腔具有有效直径。 锚固装置包括套筒，其包括限定外表面和内孔的基本上细长的主体。 锚定装置还具有包括第一端部，第二端部和第一端部和第二端部之间的中间部分的压缩构件。 压缩构件至少部分地嵌入在套筒中，使得压缩构件的第一和第二端部彼此朝向彼此的压缩导致锚定装置的内腔的至少一部分的有效直径可逆地增加。
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4.发明授权Apparatus for manufacturing an endocardial defibrillation lead with multi-lumen body and method 失效用于制造具有多腔体的心内除颤引线的装置及方法公开(公告)号：US06377857B1
公开(公告)日：2002-04-23
申请号：US09615120
申请日：2000-07-13
IPC分类号： A61N105
CPC分类号： A61N1/056 , B26D3/164 , B26D7/01 , B26F1/0015 , B26F1/0023 , B26F1/12
摘要： An implantable endocardial defibrillation lead having an elongated lead body with multiple lumens therein. Windows, cut through the lead body, provide access to selected ones of the lumens at selected locations along the lead body. In addition, a method and an apparatus for forming windows in a multilumen lead body are disclosed. A ferromagnetic stylet is inserted into a selected lumen. The lead body is oriented in a jig by application of an electromagnetic field. A grinder or punch cuts a window into the selected lumen.
摘要翻译： 一种可植入心内膜除颤引线，其具有在其中具有多个内腔的细长引线体。 通过引线主体切割的Windows可以在引线主体的选定位置访问选定的管腔。 另外，公开了一种用于在多腔体引线体中形成窗的方法和装置。 将铁磁探针插入选定的内腔。 引线体通过施加电磁场而在夹具中取向。 研磨机或冲头将窗口切入所选择的内腔。
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5.发明授权公开(公告)号：US06374488B1
公开(公告)日：2002-04-23
申请号：US09475570
申请日：2000-01-05
IPC分类号： H02R4304
CPC分类号： H02G1/128 , Y10T29/49117 , Y10T29/49174 , Y10T29/49179 , Y10T29/49187 , Y10T29/49192 , Y10T29/49194 , Y10T29/51 , Y10T29/532 , Y10T29/53209 , Y10T29/53243 , Y10T29/53265
摘要： An apparatus and method for laser stripping coated cables for endocardial defibrillation leads comprising a jig for holding at least one insulated wire, the jig having a base plate, a linear stripping area on the plate, a first clasp mounted on the plate for holding a first end of the wire, at least two primary pins mounted on the plate on a first side of the linear stripping area, at least one secondary pin mounted on the plate on a second side of the linear stripping area, and a second clasp mounted on the plate for holding a second end of the wire; and a laser effective to remove insulation from the insulated wire, the laser being mounted to effectively remove insulation in the linear stripping area.
摘要翻译： 一种用于心内除颤引线的激光剥离涂覆电缆的装置和方法，包括用于保持至少一个绝缘线的夹具，所述夹具具有基板，板上的线性剥离区域，安装在板上用于保持第一 所述导线的端部，至少两个主销安装在所述线性剥离区域的第一侧上的所述板上，至少一个辅助销安装在所述板上，在所述线性剥离区域的第二侧上，以及第二扣环， 用于固定电线的第二端的板; 以及有效地去除绝缘线绝缘的激光器，激光器被安装以有效地去除线性剥离区域中的绝缘。
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6.发明授权Medical devices including polyisobutylene based polymers and derivatives thereof 有权医疗器械包括聚异丁烯基聚合物及其衍生物公开(公告)号：US08644952B2
公开(公告)日：2014-02-04
申请号：US12874887
申请日：2010-09-02
IPC分类号： A61N1/05
CPC分类号： A61L31/06 , A61N1/05 , C08G18/12 , C08G18/4063 , C08G18/4854 , C08G18/6204 , C08G18/6705 , C08G18/7671 , Y10T29/49204 , Y10T156/10 , C08G18/3206
摘要： The present invention is directed to a medical electrical lead including an insulative lead body formed, at least in part, from a polyisobutylene urethane, urea or urethane/urea copolymer. In some applications, the lead body can include at least one outer tubular insulator and/or an inner elongated member formed from a polyisobutylene urethane, urea or urethane/urea copolymer. Portions of the lead body formed form the polyisobutylene urethane, urea or urethane/urea copolymer can be either extruded or molded.
摘要翻译： 本发明涉及一种包括至少部分由聚异丁烯聚氨酯，尿素或氨基甲酸酯/脲共聚物形成的绝缘引线体的医用电线。 在一些应用中，引线体可以包括由聚异丁烯聚氨酯，脲或氨基甲酸酯/尿素共聚物形成的至少一个外部管状绝缘体和/或内部细长构件。 由聚异丁烯聚氨酯形成的引线体的部分可以被挤出或模制。
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7.发明授权公开(公告)号：US08326436B2
公开(公告)日：2012-12-04
申请号：US13030467
申请日：2011-02-18
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0563 , A61N1/086
摘要： Systems and methods for improving response of implantable leads to magnetic fields during medical procedures such as magnetic resonance imaging (MRI) are described. In various embodiments, the lead includes an inner conductor that is helically shaped and radially surrounded, at least in part, by one or more high-voltage conductors. The high-voltage conductor can be mechanically and/or electrically coupled, via a coupler, to the shocking coil. The pitch of the inner and/or outer conductor can be varied (e.g., continuously or at certain points) along the length of the lead. In some embodiments, the filar thickness, the pitch, and the mean coil diameter of the inner coil, the high voltage conductor coil, and the shock coil can be configured such that these coils have a desired inductance value when subjected to externally applied electromagnetic energy at radio frequencies commonly generated by MRI scanners (e.g., 40 MHz to 300 MHz).
摘要翻译： 描述了在诸如磁共振成像（MRI）的医疗过程期间改善可植入引线对磁场的响应的系统和方法。 在各种实施例中，引线包括内部导体，该内部导体至少部分由螺旋形状并且被一个或多个高压导体径向包围。 高压导体可以通过耦合器机械地和/或电耦合到震动线圈。 内导体和/或外导体的间距可以沿引线的长度变化（例如，连续地或在某些点处）。 在一些实施例中，内部线圈，高压导体线圈和冲击线圈的丝线厚度，间距和平均线圈直径可以被配置为使得当经受外部施加的电磁能量时，这些线圈具有期望的电感值 在通常由MRI扫描仪（例如，40MHz至300MHz）产生的射频上。
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公开(公告)号：US20120179221A1
公开(公告)日：2012-07-12
申请号：US13422622
申请日：2012-03-16
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565 , A61N1/362
摘要： A system for therapeutically stimulating a His bundle includes an implantable pulse generator and a multi-polar medical electrical lead. The generator is configured for subcutaneous implantation and to generate a pacing stimulus. The lead includes a connector assembly, a flexible tubular body, a distal tip assembly and coil conductors. The body extends intravascularly from the generator to a location proximate the His bundle and includes a proximal end, a distal end, and a longitudinal lumen. The tip assembly includes an electrode, a fixation helix, and a shank portion. The helix extends to a location proximate the His bundle and is operable as an electrically isolated electrode. The shank portion extends within the lumen and includes a receptacle for receiving a stylet tip. The conductors extend longitudinally through the lumen and are coupled to the electrode and the helix. One or both of the conductors defines a stylet lumen.
摘要翻译： 用于治疗性刺激His束的系统包括可植入脉冲发生器和多极医疗电引线。 发生器被配置用于皮下植入并产生起搏刺激。 引线包括连接器组件，柔性管状体，远端尖端组件和线圈导体。 身体从发生器血管内延伸到靠近His束的位置，并且包括近端，远端和纵向内腔。 尖端组件包括电极，固定螺旋和柄部分。 螺旋线延伸到靠近His束的位置，并且可操作为电隔离电极。 柄部分在内腔内延伸并且包括用于接收通球针尖端的容器。 导体纵向延伸穿过内腔，并与电极和螺旋结合。 一个或两个导体限定了探针管腔。
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公开(公告)号：US08103359B2
公开(公告)日：2012-01-24
申请号：US11750185
申请日：2007-05-17
申请人： G. Shantanu Reddy
发明人： G. Shantanu Reddy
IPC分类号： A61N1/05
CPC分类号： A61N1/37217 , A61N1/056 , A61N1/057 , A61N1/0573 , A61N1/362 , A61N1/3702 , A61N1/37205 , A61N1/375 , A61N1/37516 , A61N1/3756 , A61N2001/0585
摘要： A transvenously implantable medical device (TIMD) includes an electrical lead and a control module. The electrical lead includes one or more electrodes and is adapted for transvenous implantation. The electrical lead is also pre-biased to expand from a collapsed state to an expanded state to mechanically engage an internal wall of a blood vessel. The control module is secured to and in electrical communication with the electrical lead. The control module includes a signal management component and a power component disposed in a housing adapted for implantation into the blood vessel. The control module is adapted for at least one of stimulating and sensing a physiologic response using the one or more electrodes of the electrical lead.
摘要翻译： 可转移植入式医疗装置（TIMD）包括电引线和控制模块。 电引线包括一个或多个电极并且适于经静脉植入。 电引线也被预偏压以从折叠状态膨胀到膨胀状态以机械地接合血管的内壁。 控制模块固定在电气导线上并与电线电连通。 控制模块包括信号管理部件和设置在适于植入血管的壳体中的功率部件。 控制模块适用于使用电引线的一个或多个电极来刺激和感测生理反应中的至少一个。
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公开(公告)号：US20110197440A1
公开(公告)日：2011-08-18
申请号：US13094514
申请日：2011-04-26
IPC分类号： H01R43/20
CPC分类号： A61N1/056 , A61N1/0573 , Y10T29/49117 , Y10T29/49208
摘要： A medical electrical lead configured to be coupled to a pulse generator in a cardiac rhythm management system. The lead comprises a proximal terminal connector configured for coupling the lead to the pulse generator, and a plurality of longitudinally arranged lead segments each configured to exhibit one or more predetermined physical characteristics based on the implantation location for the respective segment. The lead segments may be pre-fabricated as separate modules optimized for the operating environment and/or delivery requirements of the respective segments. The pre-fabricated modules are longitudinally arranged and joined to form the lead.
摘要翻译： 一种医疗电引线，被配置为耦合到心律管理系统中的脉冲发生器。 引线包括被配置为将引线耦合到脉冲发生器的近端端子连接器，以及多个纵向排列的引线段，每个引导段被配置为基于相应段的注入位置呈现一个或多个预定的物理特性。 引线段可以被预制成针对各个段的操作环境和/或传送要求而优化的单独模块。 预制模块纵向排列并连接以形成引线。
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