公开(公告)号：US20240197693A1

公开(公告)日：2024-06-20

申请号：US18440652

申请日：2024-02-13

Applicant: GENENTECH, INC.

Inventor： Lin Pan ,  Dorothy Sze-Wing Cheung ,  Jeffrey Mark Harris ,  Indiana Strombom

IPC: A61K31/437 ,  A61K31/4439

CPC classification number: A61K31/437 ,  A61K31/4439

Abstract: The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.

公开(公告)号：US20190321344A1

公开(公告)日：2019-10-24

申请号：US16465015

申请日：2017-11-29

Applicant: GENENTECH, INC.

Inventor： Lin Pan ,  Dorothy Sze-Wing Cheung ,  Jeffrey Mark Harris ,  Indiana Strombom

IPC: A61K31/437 ,  A61K31/4439

Abstract: The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.

公开(公告)号：US11925624B2

公开(公告)日：2024-03-12

申请号：US17528537

申请日：2021-11-17

Applicant: GENENTECH, INC.

Inventor： Lin Pan ,  Dorothy Sze-Wing Cheung ,  Jeffrey Mark Harris ,  Indiana Strombom

IPC: A61K31/4439 ,  A61K31/437

CPC classification number: A61K31/437 ,  A61K31/4439

Abstract: The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.

公开(公告)号：US11207304B2

公开(公告)日：2021-12-28

申请号：US16465015

申请日：2017-11-29

Applicant: GENENTECH, INC.

Inventor： Lin Pan ,  Dorothy Sze-Wing Cheung ,  Jeffrey Mark Harris ,  Indiana Strombom

IPC: A61K31/437 ,  A61K31/4439

Abstract: The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.

公开(公告)号：US20240228638A1

公开(公告)日：2024-07-11

申请号：US18528122

申请日：2023-12-04

Applicant: Genentech, Inc.

Inventor： Michele Anne Grimbaldeston ,  Divya Mohan ,  Ahmed Yousuf ,  Christopher Brightling ,  Dorothy Sze-Wing Cheung ,  David Fong Choy

IPC: C07K16/28 ,  A61K39/00 ,  A61P11/00

CPC classification number: C07K16/2866 ,  A61P11/00 ,  A61K2039/505 ,  A61K2039/545

Abstract: The application describes a method of treating chronic obstructive pulmonary disease (COPD) in a patient comprising administering 476 mg of an ST2 antagonist to the patient on Day 1 of a treatment period. The application also describes methods of treating or preventing frequency of moderate to severe exacerbations in a patient having COPD comprising administering an effective amount of an ST2 antagonist to achieve a clinical improvement of at least 10%, at least 20%, at least 21%, at least 22%, at least 25%, at least 30%, at least 35%, at least 40% or at least 45% annualized exacerbation rate reduction than standard of care (SOC).

公开(公告)号：US20220184046A1

公开(公告)日：2022-06-16

申请号：US17528537

申请日：2021-11-17

Applicant: GENENTECH, INC.

Inventor： Lin Pan ,  Dorothy Sze-Wing Cheung ,  Jeffrey Mark Harris ,  Indiana Strombom

IPC: A61K31/437 ,  A61K31/4439

Abstract: The present disclosure relates to methods of administering Compound I for treating fibrotic disorders, inflammatory disorders or autoimmune disorders.