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公开(公告)号：US10765743B2
公开(公告)日：2020-09-08
申请号：US16248402
申请日：2019-01-15
Applicant: GENMAB A/S
Inventor： Esther Breij , David Satijn , Edward Norbert Van Den Brink , Dennis Verzijl , Rob N. De Jong , Paul Parren , Riemke Van Dijkhuizen Radersma
IPC: A61K39/395 , C07K16/28 , A61K47/68 , A61K39/00 , C07K16/30
Abstract: The present invention relates to anti-AXL antibodies, immunoconjugates, compositions and method of treatment of cancer with such anti-AXL antibodies, immunoconjugates, or compositions.
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公开(公告)号：US10407501B2
公开(公告)日：2019-09-10
申请号：US15110414
申请日：2015-01-08
Applicant: GENMAB A/S
Inventor： Edward Norbert Van Den Brink , Joost J. Neijssen , Aran Frank Labrijn , Joyce Meesters , Janine Schuurman , Isil Altintas , Paul Parren , Rik Rademaker
Abstract: The present invention relates to humanized or chimeric antibodies binding CD3. It furthermore relates to bispecific antibodies, compositions, pharmaceutical compositions, use of said antibodies in the treatment of a disease, and method of treatment.
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公开(公告)号：US09663578B2
公开(公告)日：2017-05-30
申请号：US14317600
申请日：2014-06-27
Applicant: GENMAB A/S
Inventor： Edward Norbert Van Den Brink , Paul Parren , Jan Van De Winkel , Aran Frank Labrijn , Frank Everhardus Martinus Rebers , Esther Cornelia Wilhelmina Breij
IPC: A61K39/395 , C07K16/28 , A61K39/00
CPC classification number: C07K16/283 , A61K2039/505 , C07K2317/21 , C07K2317/30 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/92
Abstract: Isolated monoclonal antibodies which bind to human CD32b and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
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公开(公告)号：US20240084036A1
公开(公告)日：2024-03-14
申请号：US17972867
申请日：2022-10-25
Applicant: Genmab A/S
Inventor： Joost J. NEIJSSEN , Bart De Goeij , Edward Norbert Van Den Brink , Aran Frank Labrijn , Rene Hoet , Janine Schuurman , Paul Parren , Jan Van De Winkel
IPC: C07K16/30 , A61K39/395 , A61K45/06 , A61P35/00 , C07K16/28 , C07K16/40 , G01N33/574
CPC classification number: C07K16/3076 , A61K39/3955 , A61K45/06 , A61P35/00 , C07K16/2863 , C07K16/40 , G01N33/5748 , A61K2039/505 , C07K2317/31 , C07K2317/35 , C07K2317/524 , C07K2317/526 , C07K2317/565 , C07K2317/71 , G01N2333/912
Abstract: Isolated monoclonal antibodies which bind to human c-Met, the hepatocyte growth factor receptor, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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公开(公告)号：US11613575B2
公开(公告)日：2023-03-28
申请号：US16544376
申请日：2019-08-19
Applicant: GENMAB A/S
Inventor： Edward Norbert Van Den Brink , Joost J. Neijssen , Aran Frank Labrijn , Joyce Meesters , Janine Schuurman , Isil Altintas , Paul Parren , Rik Rademaker
Abstract: The present invention relates to humanized or chimeric antibodies binding CD3. It furthermore relates to bispecific antibodies, compositions, pharmaceutical compositions, use of said antibodies in the treatment of a disease, and method of treatment.
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Patent Agency Ranking
公开(公告)号：US10590206B2
公开(公告)日：2020-03-17
申请号：US14760157
申请日：2014-01-09
Applicant: GENMAB A/S
Inventor： Aran Frank Labrijn , Joyce Meesters , Joost J. Neijssen , Edward Norbert Van Den Brink , Janine Schuurman , Paul Parren
Abstract: Described herein are, proteins comprising amino acid substitutions in at least one of a first and a second polypeptide chain. Furthermore, is described the uses and methods related to said proteins.
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公开(公告)号：US10201607B2
公开(公告)日：2019-02-12
申请号：US15938961
申请日：2018-03-28
Applicant: GENMAB A/S
Inventor： Esther Breij , David Satijn , Edward Norbert Van Den Brink , Dennis Verzijl , Rob N. De Jong , Paul Parren , Riemke Van Dijkhuizen Radersma
IPC: A61K39/00 , A61K47/68 , C07K16/28 , C07K16/30 , A61K39/395
Abstract: The present invention relates to anti-AXL antibodies, immunoconjugates, compositions and method of treatment of cancer with such anti-AXL antibodies, immunoconjugates, or compositions.
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公开(公告)号：US11512140B2
公开(公告)日：2022-11-29
申请号：US16548883
申请日：2019-08-23
Applicant: GENMAB A/S
Inventor： Joost J. Neijssen , Bart De Goeij , Edward Norbert Van Den Brink , Aran Frank Labrijn , Rene Hoet , Janine Schuurman , Paul Parren , Jan Van De Winkel
IPC: C07K16/30 , G01N33/574 , A61P35/00 , A61K39/395 , C07K16/28 , A61K45/06 , C07K16/40 , A61K39/00
Abstract: Isolated monoclonal antibodies which bind to human c-Met, the hepatocyte growth factor receptor, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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公开(公告)号：US11485796B2
公开(公告)日：2022-11-01
申请号：US16783720
申请日：2020-02-06
Applicant: GENMAB A/S
Inventor： Aran Frank Labrijn , Joyce I. Meesters , Joost J. Neijssen , Edward Norbert Van Den Brink , Janine Schuurman , Paul Parren
Abstract: Described herein are, proteins comprising amino acid substitutions in at least one of a first and a second polypeptide chain. Furthermore, is described the uses and methods related to said proteins.
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公开(公告)号：US20190160170A1
公开(公告)日：2019-05-30
申请号：US16270317
申请日：2019-02-07
Applicant: GENMAB A/S
Inventor： Esther Breij , David Satijn , Edward Norbert Van Den Brink , Dennis Verzijl , Rob N. De Jong , Paul Parren , Riemke Van Dijkhuizen Radersma
IPC: A61K39/395 , C07K16/28 , A61K47/68 , C07K16/30
Abstract: The present invention relates to anti-AXL antibodies, immunoconjugates, compositions and method of treatment of cancer with such anti-AXL antibodies, immunoconjugates, or compositions.
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