公开(公告)号：US20240132487A1

公开(公告)日：2024-04-25

申请号：US17769198

申请日：2020-10-15

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Agnes BOMBRUN ,  An CHAI ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Marion MATHYS ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

CPC classification number: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07B2200/07 ,  C07B2200/09

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20240417359A1

公开(公告)日：2024-12-19

申请号：US18703358

申请日：2022-10-20

Applicant: GIVAUDAN SA

Inventor： Nicolas COCITO ARMANlNO ,  An CHAI ,  Felix FLACHSMANN ,  Marc LINIGER ,  Lijun ZHOU

IPC: C07C51/347 ,  C11B9/00

Abstract: There is provided a compound of formula (I) which is a homoallylic ether of a phenolic fragrant compound HX and which is able to release said phenolic fragrant compound HX and optionally a further fragrant.

公开(公告)号：US20200330346A1

公开(公告)日：2020-10-22

申请号：US16321653

申请日：2017-08-14

Applicant: Givaudan SA

Inventor： YUE ZOU ,  An CHAI ,  jIE LIU ,  Lijun ZHOU

IPC: A61K8/35 ,  C11D3/50 ,  A61L9/01 ,  C11B9/00 ,  A61Q13/00

Abstract: The present invention refers to indanone derivatives of formula (I) wherein R1 is selected from hydrogen, methyl and ethyl; R2 is selected from hydrogen, methyl and ethyl, and R3 is selected from hydrogen and methyl; or R2 and R3 form together with the carbon atoms to which they are attached C3-C5 cycloalkyl; and R4 is selected from C2-C5 alkyl, C2-C5 alkenyl, C1-C4 alkoxy, C3-C5 cycloalkyl, and C3-C6 cycloalkenyl. The invention further refers to perfume compositions and fragrance applications comprising them.