公开(公告)号：US20230002334A1

公开(公告)日：2023-01-05

申请号：US17777910

申请日：2020-11-26

Applicant: Givaudan SA

Inventor： Chao WANG ,  Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Andreas GOEKE ,  Feng HUANG ,  Andreas NATSCH ,  Lijun ZHOU ,  Yue ZOU

IPC: C07D265/16 ,  C07D498/04 ,  A61Q19/00 ,  A61Q11/02

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20250057747A1

公开(公告)日：2025-02-20

申请号：US18712550

申请日：2022-11-21

Applicant: GIVAUDAN SA

Inventor： Nicolas COCITO ARMANINO ,  Chao WANG

IPC: A61K8/49 ,  A61Q13/00 ,  C07D313/00 ,  C11D3/20 ,  C11D3/50

Abstract: Disclosed are oxa macrocyclic ketones of formula (I) possessing musky, powdery, nitro musk odor characteristics.

公开(公告)号：US20240132487A1

公开(公告)日：2024-04-25

申请号：US17769198

申请日：2020-10-15

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Agnes BOMBRUN ,  An CHAI ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Marion MATHYS ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

CPC classification number: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07B2200/07 ,  C07B2200/09

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20230098332A1

公开(公告)日：2023-03-30

申请号：US17800049

申请日：2021-03-04

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Changming DING ,  Roger EMTER ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D295/096 ,  C07D309/04 ,  C07D335/02 ,  C07D279/12 ,  C07D241/04

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucosa.

公开(公告)号：US20240294470A1

公开(公告)日：2024-09-05

申请号：US18569975

申请日：2022-06-16

Applicant: Givaudan SA

Inventor： Chao WANG ,  Lijun ZHOU ,  Felix FLACHSMANN

IPC: C07C291/02 ,  A61K8/41 ,  A61Q5/02 ,  C07C45/42 ,  C07D307/52 ,  C07D317/58 ,  C11B9/00 ,  C11D3/30 ,  C11D3/50

CPC classification number: C07C291/02 ,  A61K8/41 ,  A61Q5/02 ,  C07C45/42 ,  C07D307/52 ,  C07D317/58 ,  C11B9/0007 ,  C11D3/30 ,  C11D3/50 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16

Abstract: It is described the use of a compound according to formula (I)




as precursor in perfumery for generating a ketone or aldehyde of formula (II)