公开(公告)号：US11708394B2

公开(公告)日：2023-07-25

申请号：US17265610

申请日：2019-08-09

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Maria Scarselli ,  Daniele Veggi

IPC: C07K14/22 ,  A61P31/04 ,  A61K39/095

CPC classification number: C07K14/22 ,  A61K39/095 ,  A61P31/04 ,  C07K2319/00

Abstract: The present invention provides mutated fHbp polypeptides and fusion proteins comprising said mutated fHbp polypeptides that are useful as components of immunogenic compositions for immunizing against Neisseria meningitidis infection.