公开(公告)号：US09642904B2

公开(公告)日：2017-05-09

申请号：US14961772

申请日：2015-12-07

Applicant: GlaxoSmithKline Biologicals SA

Inventor： Fabio Bagnoli ,  Massimiliano Biagini ,  Luigi Fiaschi ,  Guido Grandi ,  Ravi Pratap Narayan Mishra ,  Nathalie Norais ,  Maria Scarselli

IPC: A61K39/085 ,  C07K14/31 ,  A61K39/00

CPC classification number: A61K39/085 ,  A61K39/00 ,  C07K14/31 ,  C07K2319/00

Abstract: An effective Staphylococcus aureus vaccine may require several antigenic components, and so various combinations of S. aureus antigens are identified for use in immunisation. These polypeptides may optionally be used in combination with S. aureus saccharides.

公开(公告)号：US10195263B2

公开(公告)日：2019-02-05

申请号：US15589834

申请日：2017-05-08

Applicant: GlaxoSmithKline Biologicals SA

Inventor： Fabio Bagnoli ,  Massimiliano Biagini ,  Luigi Fiaschi ,  Guido Grandi ,  Ravi Pratap Narayan Mishra ,  Nathalie Norais ,  Maria Scarselli

IPC: A61K39/085 ,  C07K14/31 ,  A61K39/00

Abstract: An effective Staphylococcus aureus vaccine may require several antigenic components, and so various combinations of S. aureus antigens are identified for use in immunisation. These polypeptides may optionally be used in combination with S. aureus saccharides.

公开(公告)号：US10328140B2

公开(公告)日：2019-06-25

申请号：US15127537

申请日：2015-03-24

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Fabio Bagnoli ,  Luigi Fiaschi ,  Maria Scarselli

IPC: A61K39/085 ,  A61K39/00 ,  A61K49/00 ,  C07K14/31

Abstract: Mutant protein A of Staphylococcus aureus (SpA) with decreased affinity for the Fcγ portion of human IgG is provided.