公开(公告)号：US20230266317A1

公开(公告)日：2023-08-24

申请号：US17641315

申请日：2020-09-09

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Michael CHAPLET ,  Nathalie NORAIS ,  Simona RONDINI ,  Silvia ROSSI PACCANI

IPC: G01N33/569 ,  C07K16/12

CPC classification number: G01N33/56911 ,  C07K16/1203 ,  G01N2333/212 ,  C07K2317/33

Abstract: The present invention relates to in vitro assays, more particularly ELISA assays. Said ELISA assays comprise antibodies capable of binding Ubiquitous surface protein A2 (UspA2) from Moraxella catarrhalis. The present invention relates to assays for assessing the binding of antibodies to UspA2 and the relative potency of vaccine test samples comprising UspA2. In particular, the invention relates to in vitro relative potency assays used in the release of vaccine that comprises UspA2 to the public.