公开(公告)号：US20220184158A1

公开(公告)日：2022-06-16

申请号：US17416642

申请日：2019-12-20

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Jean-Francois TOUSSAINT ,  Vanesa BOL

IPC: A61K35/768 ,  A61K39/12 ,  A61K38/17 ,  A61P35/00 ,  C12N7/00

Abstract: There is provided inter alia a method of treating cancer in a mammal, said method comprising the steps of: (i) administering to the mammal a first composition comprising an antigen or comprising a nucleic acid encoding an antigen and (ii) administering to the mammal a second composition comprising an oncolytic virus wherein the oncolytic virus comprises a nucleic acid encoding the antigen.