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公开(公告)号:US20190119223A1
公开(公告)日:2019-04-25
申请号:US16094910
申请日:2017-05-11
Inventor: Brian Alvin JOHNS , Wieslaw Mieczyslaw KAZMIERSKI , Martha Alicia DE LA ROSA , Vicente SAMANO
IPC: C07D257/04 , C07C323/63 , C07D403/12 , C07D401/12 , C07D413/12 , C07D405/12 , C07D417/12 , C07D285/08 , C07C323/42 , C07C323/45 , C07F9/6524 , C07D401/04 , C07D401/10 , C07D249/06 , C07D249/08 , C07D271/06
CPC classification number: C07D257/04 , C07C323/42 , C07C323/45 , C07C323/63 , C07D249/06 , C07D249/08 , C07D271/06 , C07D285/08 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07F9/6524
Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.
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公开(公告)号:US20200165280A1
公开(公告)日:2020-05-28
申请号:US16618537
申请日:2018-06-27
Inventor: Martha Alicia DE LA ROSA , Hongfeng DENG , Ghotas EVINDAR , Wieslaw Mieczyslaw KAZMIERSKI , John Franklin MILLER , Vicente SAMANO , Yoshiaki WASHIO , Bing XIA
IPC: C07F9/6561 , C07D491/107 , C07D491/20
Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.
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公开(公告)号:US20180298035A1
公开(公告)日:2018-10-18
申请号:US15578861
申请日:2016-06-30
Abstract: Provided are compounds of formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the progression of AIDS and general immunosuppression.
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公开(公告)号:US20240182473A1
公开(公告)日:2024-06-06
申请号:US18508355
申请日:2023-11-14
Inventor: Martha Alicia DE LA ROSA , John F. MILLER , B. Narasimhulu NAIDU , Vicente SAMANO , David TEMELKOFF , Emile Johann VELTHUISEN
IPC: C07D473/34 , A61K9/00 , A61K45/06 , A61P31/18 , C07D487/04
CPC classification number: C07D473/34 , A61K9/0019 , A61K45/06 , A61P31/18 , C07D487/04
Abstract: The invention relates to compounds of Formula (I), (Ia), (II) or (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
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公开(公告)号:US20220411425A1
公开(公告)日:2022-12-29
申请号:US17335145
申请日:2021-06-01
Inventor: Martha Alicia DE LA ROSA , John F. MILLER , B. Narasimhulu NAIDU , Vicente SAMANO , David TEMELKOFF , Emile Johann VELTHUISEN
IPC: C07D473/34 , A61K9/00 , A61K45/06
Abstract: The invention relates to a compound having the structure: or a pharmaceutically acceptable salt thereof, along with pharmaceutical compositions and therapeutic methods thereof.
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公开(公告)号:US20210078988A1
公开(公告)日:2021-03-18
申请号:US16618830
申请日:2018-06-27
Inventor: Ghotas EVINDAR , Wieslaw Mieczyslaw KAZMIERSKI , John Franklin MILLER , Vicente SAMANO , Lita SUWANDI , David TEMELKOFF , Yoshiaki WASHIO , Bing XIA
IPC: C07D413/14 , C07D409/12 , C07D211/26 , C07D409/14 , C07D401/06 , C07D413/06 , C07D413/12 , C07D401/12 , C07D405/12 , C07D417/12 , C07D211/96
Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.
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