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公开(公告)号：US20190031698A1
公开(公告)日：2019-01-31
申请号：US16082848
申请日：2017-03-07
Applicant: GLYCOM A/S
Inventor： Martin MATWIEJUK , Nikolay KHANZHIN , Pierre CHASSAGNE , Markus Jondelius HEDEROS
Abstract: The present invention relates to a method for separating sialylated oligosaccharides from a fermentation broth in which they are produced by a genetically modified microorganism The separation comprises the steps of: i) ultrafiltration; ii) nano-filtration; iii) optionally, activated charcoal treatment; and iv) treatment with strong anion and/or cation exchange resin.
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