公开(公告)号：US20190276446A1

公开(公告)日：2019-09-12

申请号：US16421197

申请日：2019-05-23

Applicant: GUANGZHOU INNOCARE PHARMA TECH CO., LTD.

Inventor： Xiangyang CHEN ,  Yingxiang GAO ,  Chong LIU ,  Haihong NI ,  Mark MULVIHILL

IPC: C07D417/04 ,  C07D401/12 ,  C07D295/185 ,  C07D211/34 ,  C07D277/56 ,  C07D401/14 ,  C07D403/04 ,  C07D401/04 ,  C07D231/14 ,  C07D213/82 ,  C07D413/04

Abstract: Compounds of Formula I, as shown below and defined herein: and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).

公开(公告)号：US20220298153A1

公开(公告)日：2022-09-22

申请号：US17804012

申请日：2022-05-25

Applicant: GUANGZHOU INNOCARE PHARMA TECH CO., LTD.

Inventor： Xiangyang CHEN ,  Yingxiang GAO ,  Chong LIU ,  Haihong NI ,  Mark MULVIHILL

IPC: C07D417/04 ,  C07D401/14 ,  C07D213/82 ,  C07D231/14 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D277/56 ,  C07D211/34 ,  C07D295/185 ,  C07D401/12

Abstract: Compounds of Formula I, as shown below and defined herein: and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).

公开(公告)号：US20250059176A1

公开(公告)日：2025-02-20

申请号：US18938776

申请日：2024-11-06

Applicant: GUANGZHOU INNOCARE PHARMA TECH CO., LTD.

Inventor： Xiangyang CHEN ,  Yingxiang GAO ,  Chong LIU ,  Haihong NI

IPC: C07D417/04 ,  A61K31/444 ,  A61P35/00 ,  C07D211/34 ,  C07D213/82 ,  C07D231/14 ,  C07D277/56 ,  C07D295/185 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D413/04

Abstract: Compounds of Formula I, as shown below and defined herein: and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).

公开(公告)号：US20240101545A1

公开(公告)日：2024-03-28

申请号：US18496692

申请日：2023-10-27

Applicant: GUANGZHOU INNOCARE PHARMA TECH CO., LTD.

Inventor： Xiangyang CHEN ,  Yingxiang GAO ,  Chong LIU ,  Haihong NI

IPC: C07D417/04 ,  A61K31/444 ,  A61P35/00 ,  C07D211/34 ,  C07D213/82 ,  C07D231/14 ,  C07D277/56 ,  C07D295/185 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D413/04

CPC classification number: C07D417/04 ,  A61K31/444 ,  A61P35/00 ,  C07D211/34 ,  C07D213/82 ,  C07D231/14 ,  C07D277/56 ,  C07D295/185 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D413/04

Abstract: Compounds of Formula I, as shown below and defined herein:




and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).