-
1.发明授权MRP-related ABC transporter encoding nucleic acids and methods of use thereof 失效MRP相关ABC转运蛋白编码核酸及其使用方法公开(公告)号：US07312026B2
公开(公告)日：2007-12-25
申请号：US10889503
申请日：2004-07-12
申请人： Gary Kruh , Kun Lee , Martin Belinsky , Lisa Bain
发明人： Gary Kruh , Kun Lee , Martin Belinsky , Lisa Bain
CPC分类号： C07K14/705 , A01K2217/05
摘要： Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
摘要翻译： 本文提供新的人类MOAT基因及其编码的蛋白质。 由公开的核酸序列编码的与MRP相关的ABC转运蛋白在来自肿瘤细胞的药理学有益试剂的流出中起关键作用。 MOAT基因及其编码的蛋白为抑制恶性细胞异常生长的抗癌药物的设计提供了有价值的治疗靶点。
-
2.发明授权MPR-related ABC transporter encoding nucleic acids and methods of use thereof 有权Mrp相关ABC转运蛋白编码核酸及其使用方法公开(公告)号：US06803184B1
公开(公告)日：2004-10-12
申请号：US09647140
申请日：2000-09-27
IPC分类号： C12Q100
CPC分类号： C07K14/705 , A01K2217/05
摘要： Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded protein provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
摘要翻译： 本文提供新的人类MOAT基因及其编码的蛋白质。 由公开的核酸序列编码的与MRP相关的ABC转运蛋白在来自肿瘤细胞的药理学有益试剂的流出中起关键作用。 MOAT基因及其编码的蛋白为抑制恶性细胞异常生长的抗癌药物的设计提供了有价值的治疗靶点。
-
3.发明申请MRP-related ABC transporter encoding nucleic acids and methods of use thereof 失效MRP相关ABC转运蛋白编码核酸及其使用方法公开(公告)号：US20050063968A1
公开(公告)日：2005-03-24
申请号：US10889503
申请日：2004-07-12
申请人： Gary Kruh , Kun Lee , Martin Belinsky , Lisa Bain
发明人： Gary Kruh , Kun Lee , Martin Belinsky , Lisa Bain
IPC分类号： C07K14/705 , C12Q1/68 , A61K39/395 , C07H21/04 , C07K16/28
CPC分类号： C07K14/705 , A01K2217/05
摘要： Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
摘要翻译： 本文提供新的人类MOAT基因及其编码的蛋白质。 由公开的核酸序列编码的与MRP相关的ABC转运蛋白在来自肿瘤细胞的药理学有益试剂的流出中起关键作用。 MOAT基因及其编码的蛋白为抑制恶性细胞异常生长的抗癌药物的设计提供了有价值的治疗靶点。
-
-
搜索结果
3 条记录 (耗时 0.018 秒)
