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公开(公告)号:US20120201844A1
公开(公告)日:2012-08-09
申请号:US13333123
申请日:2011-12-21
申请人: Gary W. ZLOTNICK , Leah Diane FLETCHER , John Erwin Farley , Liesel A. BERNFIELD , Robert J. ZAGURSKY , Benjamin J. METCALF
发明人: Gary W. ZLOTNICK , Leah Diane FLETCHER , John Erwin Farley , Liesel A. BERNFIELD , Robert J. ZAGURSKY , Benjamin J. METCALF
IPC分类号: A61K39/095 , A61P31/04 , A61P37/04 , C07K14/22
CPC分类号: A61K39/095 , A61K39/00 , A61K39/39 , A61K47/543 , A61K47/646 , A61K2039/505 , A61K2039/53 , A61K2039/54 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , A61K2039/58 , A61K2039/6087 , C07K14/22 , C07K16/1217 , C12N9/2417 , C12N9/2465 , C12N9/2471 , G01N33/56911 , G01N2333/22 , Y10S530/825
摘要: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.