公开(公告)号：US20200172911A1

公开(公告)日：2020-06-04

申请号：US16724054

申请日：2019-12-20

Applicant: Genentech, Inc.

Inventor： Yingnan Zhang ,  Baris Bingol ,  Jacob Corn

IPC: C12N15/113 ,  A61K31/7088 ,  A61K45/06 ,  C07K7/08

Abstract: Inhibitors of USP30 and methods of using inhibitors of USP30 are provided. In some embodiments, methods of treating conditions involving mitochondrial defects are provided.

公开(公告)号：US20150344888A1

公开(公告)日：2015-12-03

申请号：US14659204

申请日：2015-03-16

Applicant: GENENTECH, INC.

Inventor： Yingnan Zhang ,  Baris Bingol ,  Jacob Corn

IPC: C12N15/113 ,  A61K38/10 ,  C07K7/08 ,  A61K31/7088 ,  A61K45/06

CPC classification number: C12N15/1137 ,  A61K31/7088 ,  A61K38/00 ,  A61K45/06 ,  C07K7/08 ,  C12N2310/11 ,  C12N2310/14 ,  C12Y301/02015 ,  C12Y304/19012 ,  A61K2300/00

Abstract: Inhibitors of USP30 and methods of using inhibitors of USP30 are provided. In some embodiments, methods of treating conditions involving mitochondrial defects are provided.

Abstract translation: 提供USP30的抑制剂和使用USP30抑制剂的方法。 在一些实施方案中，提供了治疗涉及线粒体缺陷的病症的方法。