公开(公告)号：US12030926B2

公开(公告)日：2024-07-09

申请号：US17171962

申请日：2021-02-09

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Whitney Shatz ,  Domingos Ng

IPC: C07K16/00 ,  C07K16/46 ,  C12N15/79 ,  C12N15/90

CPC classification number: C07K16/00 ,  C07K16/468 ,  C07K2317/14 ,  C07K2317/31 ,  C07K2317/52 ,  C07K2317/526 ,  C07K2317/53 ,  C12N15/79 ,  C12N15/907

Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes located on a single molecule or located on different molecules.

公开(公告)号：US10941190B2

公开(公告)日：2021-03-09

申请号：US15344123

申请日：2016-11-04

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Whitney Shatz ,  Domingos Ng

IPC: C07K16/00 ,  C07K16/46 ,  C07K1/00 ,  C07K1/02 ,  C12P21/02 ,  C12P21/00 ,  C12N15/79 ,  C12N15/90

Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes located on a single molecule or located on different molecules.