公开(公告)号：US20240239766A1

公开(公告)日：2024-07-18

申请号：US18584298

申请日：2024-02-22

Applicant: Genentech, Inc.

Inventor： Steven John MCKERRALL ,  Daniel Fred ORTWINE ,  Philippe BERGERON ,  Ramsay BEVERIDGE ,  Elise GHIRO ,  Kwong Wah LAI ,  Guqin SHI

IPC: C07D401/12 ,  A61K31/454 ,  A61K31/506 ,  A61P17/04 ,  A61P29/00 ,  C07D401/14 ,  C07D405/14 ,  C07D413/12 ,  C07D417/12

CPC classification number: C07D401/12 ,  A61K31/454 ,  A61K31/506 ,  A61P17/04 ,  A61P29/00 ,  C07D401/14 ,  C07D405/14 ,  C07D413/12 ,  C07D417/12

Abstract: The invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein Z1, Z2, R3-R8, RA, ring A, and n have the meanings described herein, and compositions containing such compounds and methods for using such compounds and compositions for the treatment of pain.