公开(公告)号：US20190233491A1

公开(公告)日：2019-08-01

申请号：US16128008

申请日：2018-09-11

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Ganesh A. Kolumam ,  Xiaoting Wang ,  Jed Ross ,  Nicholas Van Bruggen ,  Wyne P. Lee

IPC: C07K14/54 ,  A61K38/20 ,  A61K47/38 ,  C07K16/28

CPC classification number: C07K14/54 ,  A61K38/00 ,  A61K38/20 ,  A61K47/38 ,  C07K16/2866 ,  C07K2319/30

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US11136365B2

公开(公告)日：2021-10-05

申请号：US16196823

申请日：2018-11-20

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Ganesh A. Kolumam ,  Xiaoting Wang ,  Jed Ross ,  Nicholas Van Bruggen

IPC: C07K14/54 ,  C07K16/28 ,  A61K38/20 ,  A61K47/38 ,  A61K38/00

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US20190177390A1

公开(公告)日：2019-06-13

申请号：US16196936

申请日：2018-11-20

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Ganesh A. Kolumam ,  Xiaoting Wang ,  Jed Ross ,  Nicholas Van Bruggen ,  Wyne P. Lee

IPC: C07K14/54 ,  A61K38/20 ,  A61K47/38 ,  C07K16/28

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US10584155B2

公开(公告)日：2020-03-10

申请号：US15801867

申请日：2017-11-02

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Ganesh A. Kolumam ,  Xiaoting Wang ,  Jed Ross ,  Nicholas Van Bruggen ,  Wyne P. Lee

IPC: A61K38/20 ,  C07K14/54 ,  C07K16/28 ,  A61K47/38 ,  A61K38/00

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US20190177387A1

公开(公告)日：2019-06-13

申请号：US16196743

申请日：2018-11-20

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Ganesh A. Kolumam ,  Xiaoting Wang ,  Jed Ross ,  Nicholas Van Bruggen ,  Wyne P. Lee

IPC: C07K14/54 ,  A61K38/20 ,  A61K47/38 ,  C07K16/28

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.