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公开(公告)号:US20210171571A1
公开(公告)日:2021-06-10
申请号:US17145235
申请日:2021-01-08
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20140199321A1
公开(公告)日:2014-07-17
申请号:US14165098
申请日:2014-01-27
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona M. O'Leary
IPC: A61K47/18 , A61K39/395
CPC classification number: A61K47/183 , A61K39/3955 , A61K39/39591 , A61K47/18 , C07K16/065 , C07K16/2863 , C07K16/32 , C07K2317/24 , C07K2317/76
Abstract: Methods for stabilizing polypeptides, such as anti-HER2 antibodies, which have been exposed to urea.
Abstract translation: 用于稳定暴露于尿素的多肽例如抗HER2抗体的方法。
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公开(公告)号:US20210130399A1
公开(公告)日:2021-05-06
申请号:US17145233
申请日:2021-01-08
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20180244715A1
公开(公告)日:2018-08-30
申请号:US15836695
申请日:2017-12-08
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
CPC classification number: C07K1/18 , B01D15/362 , B01D15/363 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/565 , C07K2317/76
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20190352332A1
公开(公告)日:2019-11-21
申请号:US16533610
申请日:2019-08-06
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US09868760B2
公开(公告)日:2018-01-16
申请号:US14218445
申请日:2014-03-18
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
CPC classification number: C07K1/18 , B01D15/362 , B01D15/363 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/565 , C07K2317/76
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20150072918A1
公开(公告)日:2015-03-12
申请号:US14218445
申请日:2014-03-18
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
CPC classification number: C07K1/18 , B01D15/362 , B01D15/363 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/565 , C07K2317/76
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
Abstract translation: 描述了通过离子交换色谱法纯化多肽的方法,其中使用梯度洗涤来从一种或多种污染物中分离感兴趣的多肽。
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公开(公告)号:US20210130398A1
公开(公告)日:2021-05-06
申请号:US17145231
申请日:2021-01-08
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20190352333A1
公开(公告)日:2019-11-21
申请号:US16533621
申请日:2019-08-06
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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公开(公告)号:US20190352331A1
公开(公告)日:2019-11-21
申请号:US16533593
申请日:2019-08-06
Applicant: Genentech, Inc.
Inventor: Jefferson C. Emery , Paul J. McDonald , Rhona O'Leary
Abstract: A method for purifying a polypeptide by ion exchange chromatography is described in which a gradient wash is used to resolve a polypeptide of interest from one or more contaminants.
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