公开(公告)号：US20240228463A1

公开(公告)日：2024-07-11

申请号：US18584311

申请日：2024-02-22

Applicant: Genentech, Inc.

Inventor： Marc KSCHONSAK ,  Steven John MCKERRALL ,  Daniel Fred ORTWINE ,  Jian Mehr-Dean PAYANDEH ,  Benjamin Douglas SELLERS ,  John C. TELLIS ,  Matthew VOLGRAF ,  Philippe BERGERON ,  Claudio CIFERRI ,  Peter Scott DRAGOVICH

IPC: C07D401/12 ,  A61K31/18 ,  A61P25/04 ,  C07C311/51 ,  C07D211/96 ,  C07D277/44 ,  C07D277/82 ,  C07D295/26 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

CPC classification number: C07D401/12 ,  A61K31/18 ,  A61P25/04 ,  C07C311/51 ,  C07D211/96 ,  C07D277/44 ,  C07D277/82 ,  C07D295/26 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

Abstract: The invention provides compounds of formulae I, II, IIa, and III:




and pharmaceutically acceptable salts thereof, as well as compositions containing such compounds and methods for using such compounds and compositions.