公开(公告)号：US10689325B2

公开(公告)日：2020-06-23

申请号：US16415612

申请日：2019-05-17

Applicant: Genentech, Inc.

Inventor： Stephan Bachmann ,  Serena Maria Fantasia ,  Michael Jansen ,  Stefan Koenig ,  Xin Linghu ,  Sebastian Rieth ,  Nathaniel L. Segraves ,  Andreas Zogg

IPC: C07D498/22 ,  C07C213/00 ,  C07C201/12 ,  C07C213/02 ,  C07K16/12 ,  C07D498/04 ,  A61K47/68 ,  C07D498/18 ,  A61K39/00

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

公开(公告)号：US10336683B2

公开(公告)日：2019-07-02

申请号：US15448894

申请日：2017-03-03

Applicant: Genentech, Inc.

Inventor： Stephan Bachmann ,  Serena Maria Fantasia ,  Michael Jansen ,  Stefan Koenig ,  Xin Linghu ,  Sebastian Rieth ,  Nathaniel L. Segraves ,  Andreas Zogg

IPC: C07D498/22 ,  C07C213/00 ,  C07D498/18 ,  C07K16/12 ,  C07C201/12 ,  C07C213/02 ,  C07D498/04 ,  A61K47/68 ,  A61K39/00

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

公开(公告)号：US20170252457A1

公开(公告)日：2017-09-07

申请号：US15448894

申请日：2017-03-03

Applicant: Genentech, Inc.

Inventor： Stephan Bachmann ,  Serena Maria Fantasia ,  Michael Jansen ,  Stefan Koenig ,  Xin Linghu ,  Sebastian Rieth ,  Nathaniel L. Segraves ,  Andreas Zogg

IPC: A61K47/48 ,  C07K16/12 ,  C07D498/18 ,  C07C213/00 ,  C07K19/00

CPC classification number: C07C213/00 ,  A61K47/6803 ,  A61K47/6835 ,  A61K2039/505 ,  C07C201/12 ,  C07C213/02 ,  C07D498/04 ,  C07D498/18 ,  C07K16/1267 ,  C07K16/1271 ,  C07K2317/77 ,  C07C205/37 ,  C07C215/78

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

公开(公告)号：US20190270695A1

公开(公告)日：2019-09-05

申请号：US16415612

申请日：2019-05-17

Applicant: Genentech, Inc.

Inventor： Stephan Bachmann ,  Serena Maria Fantasia ,  Michael Jansen ,  Stefan Koenig ,  Xin Linghu ,  Sebastian Rieth ,  Nathaniel L. Segraves ,  Andreas Zogg

IPC: C07C213/00 ,  A61K47/68 ,  C07D498/04 ,  C07D498/18 ,  C07K16/12 ,  C07C213/02 ,  C07C201/12

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.