公开(公告)号：US20160168261A1

公开(公告)日：2016-06-16

申请号：US14953763

申请日：2015-11-30

Applicant: Genentech, Inc.

Inventor： Mark DENNIS ,  Jan MARIK ,  Paul POLAKIS ,  Bonnee RUBINFELD ,  Simon WILLIAMS

IPC: C07K16/30 ,  A61K51/10 ,  C07K16/40

CPC classification number: C07K16/40 ,  A61K47/6811 ,  A61K47/6871 ,  A61K51/1072 ,  A61K51/1075 ,  A61K51/1093 ,  A61K51/1096 ,  A61K2039/505 ,  C07B59/008 ,  C07B2200/05 ,  C07K16/3069 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/92 ,  G01N33/534 ,  G01N33/57492 ,  G01N33/60 ,  G01N33/6893

Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.

公开(公告)号：US20170121424A1

公开(公告)日：2017-05-04

申请号：US15289485

申请日：2016-10-10

Applicant: Genentech, Inc.

Inventor： Mark DENNIS ,  Jan MARIK ,  Paul POLAKIS ,  Bonnee RUBINFELD ,  Simon WILLIAMS

IPC: C07K16/40 ,  C07B59/00 ,  G01N33/574 ,  G01N33/534 ,  G01N33/60 ,  A61K51/10 ,  C07K16/30

CPC classification number: C07K16/40 ,  A61K47/6811 ,  A61K47/6871 ,  A61K51/1072 ,  A61K51/1075 ,  A61K51/1093 ,  A61K51/1096 ,  A61K2039/505 ,  C07B59/008 ,  C07B2200/05 ,  C07K16/3069 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/92 ,  G01N33/534 ,  G01N33/57492 ,  G01N33/60 ,  G01N33/6893

Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.