公开(公告)号：US09891192B2

公开(公告)日：2018-02-13

申请号：US14277830

申请日：2014-05-15

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447 ,  G06T7/00

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.

公开(公告)号：US09436866B2

公开(公告)日：2016-09-06

申请号：US14449916

申请日：2014-08-01

Applicant: General Electric Company

Inventor： Aaron Judy Couture ,  Faisal Ahmed Syud ,  John Brian Hewgley ,  Yu Zhao

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06K9/00127 ,  G01N15/1434 ,  G01N15/1463 ,  G01N21/255 ,  G01N21/6456 ,  G01N21/76 ,  G01N2015/1006 ,  G01N2015/1486 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10064

Abstract: A flat panel imaging system for imaging cells provided on a cell medium is disclosed. The system includes a housing having a base portion and a lid that collectively form a closed environment to exclude external sources of light, and a flat panel detector encased in the base portion and having an array of pixels each including a photodiode and transistor. The system also includes a first light source that illuminates cells on the cell medium to excite at least a portion of the cells and cause those cells to generate photons that are captured by the array of pixels and a second light source to illuminate cells on the cell medium with a light different from the light from the first light source and that provides for a capturing of photons representative of photons transmitted through the cells on the cell medium.

Abstract translation: 公开了一种用于在细胞培养基上提供成像细胞的平板成像系统。 该系统包括壳体，其具有共同形成封闭环境以排除外部光源的基部和盖子，以及封装在基部中并具有每个包括光电二极管和晶体管的像素阵列的平板检测器。 该系统还包括照亮细胞介质上的细胞以激发细胞的至少一部分的第一光源，并使这些细胞产生由像素阵列捕获的光子和第二光源以照射细胞上的细胞 具有与来自第一光源的光不同的光的介质，并且其提供代表透射通过细胞介质上的细胞的光子的光子的捕获。

公开(公告)号：US20160034745A1

公开(公告)日：2016-02-04

申请号：US14449916

申请日：2014-08-01

Applicant: General Electric Company

Inventor： Aaron Judy Couture ,  Faisal Ahmed Syud ,  John Brian Hewgley ,  Yu Zhao

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06K9/00127 ,  G01N15/1434 ,  G01N15/1463 ,  G01N21/255 ,  G01N21/6456 ,  G01N21/76 ,  G01N2015/1006 ,  G01N2015/1486 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10064

Abstract: A flat panel imaging system for imaging cells provided on a cell medium is disclosed. The system includes a housing having a base portion and a lid that collectively form a closed environment to exclude external sources of light, and a flat panel detector encased in the base portion and having an array of pixels each including a photodiode and transistor. The system also includes a first light source that illuminates cells on the cell medium to excite at least a portion of the cells and cause those cells to generate photons that are captured by the array of pixels and a second light source to illuminate cells on the cell medium with a light different from the light from the first light source and that provides for a capturing of photons representative of photons transmitted through the cells on the cell medium.

Abstract translation: 公开了一种用于在细胞培养基上提供成像细胞的平板成像系统。 该系统包括壳体，其具有共同形成封闭环境以排除外部光源的基部和盖子，以及封装在基部中并具有每个包括光电二极管和晶体管的像素阵列的平板检测器。 该系统还包括照亮细胞介质上的细胞以激发细胞的至少一部分的第一光源，并使这些细胞产生由像素阵列捕获的光子和第二光源以照射细胞上的细胞 具有与来自第一光源的光不同的光的介质，并且其提供代表透射通过细胞介质上的细胞的光子的光子的捕获。

公开(公告)号：US09383336B2

公开(公告)日：2016-07-05

申请号：US14245041

申请日：2014-04-04

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.

Abstract translation: 公开了一种用于在荧光凝胶成像中产生数字图像的系统和方法。 该方法包括提供凝胶样品并将凝胶样品放置在具有阵列的光电二极管和晶体管的平板检测器上，所述光电二极管和晶体管收集凝胶样品产生的光。 使用集成到平板成像系统中的光源照射凝胶样品，然后响应于由光源提供的光的凝胶样品的激发而响应于凝胶样品发出的光，然后用凝胶样品发射的光 由平板检测器的光电二极管阵列收集，并转换成电荷以产生光数据。 然后处理光数据以产生凝胶样品的数字图像。

公开(公告)号：US20150285763A1

公开(公告)日：2015-10-08

申请号：US14245041

申请日：2014-04-04

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.

公开(公告)号：US20150285761A1

公开(公告)日：2015-10-08

申请号：US14264133

申请日：2014-04-29

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.

Abstract translation: 公开了一种用于在荧光凝胶成像中产生数字图像的系统和方法。 该方法包括提供凝胶样品并将凝胶样品放置在具有阵列的光电二极管和晶体管的平板检测器上，所述光电二极管和晶体管收集凝胶样品产生的光。 使用集成到平板成像系统中的光源照射凝胶样品，然后响应于由光源提供的光的凝胶样品的激发而响应于凝胶样品发出的光，然后用凝胶样品发射的光 由平板检测器的光电二极管阵列收集，并转换成电荷以产生光数据。 然后处理光数据以产生凝胶样品的数字图像。

公开(公告)号：US09594053B2

公开(公告)日：2017-03-14

申请号：US14264133

申请日：2014-04-29

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.

Abstract translation: 公开了一种用于在荧光凝胶成像中产生数字图像的系统和方法。 该方法包括提供凝胶样品并将凝胶样品放置在具有阵列的光电二极管和晶体管的平板检测器上，所述光电二极管和晶体管收集凝胶样品产生的光。 使用集成到平板成像系统中的光源照射凝胶样品，然后响应于由光源提供的光的凝胶样品的激发而响应于凝胶样品发出的光，然后用凝胶样品发射的光 由平板检测器的光电二极管阵列收集，并转换成电荷以产生光数据。 然后处理光数据以产生凝胶样品的数字图像。

公开(公告)号：US20150285762A1

公开(公告)日：2015-10-08

申请号：US14277830

申请日：2014-05-15

Applicant: General Electric Company

Inventor： Feng Pan ,  Brian David Yanoff ,  Aaron Judy Couture ,  Hakan Erik Roos ,  Yu Zhao

IPC: G01N27/447

CPC classification number: G01N27/44726 ,  G01N27/44721 ,  G06T7/0012

Abstract: A system and method for generating a digital image in fluorescence gel imaging is disclosed. The method includes providing a gel sample and placing the gel sample on a flat panel detector having array of photodiodes and transistors that collect light generated from the gel sample. The gel sample is illuminated using a light source integrated into the flat panel imaging system and light emitted by the gel sample responsive to an excitation of the gel sample by light provided by the light source is then collected, with the light emitted by the gel sample being collected by the array of photodiodes of the flat panel detector and converted to electric charges to generate light data. The light data is then processed to generate a digital image of the gel sample.